くすりのしおり

External
Revised: 8/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Epiduo Gel
 Active ingredient:
Adapalene
Benzoyl peroxide
 Dosage form:
white to faint yellow opaque gel
 Print on wrapping:

Effects of this medicine

This medicine is a combination gel containing adapalene and benzoyl peroxide. Adapalene suppresses differentiation of epidermal keratinocytes to prevent obstruction of the skin pores and suppress formation of pimples (acne). Benzoyl peroxide inhibits proliferation of bacteria that cause comedo (acne), and also improves obstruction of the pores by loosening bindings of keratinocytes. As a result, inflammatory rash (redheads) and non-inflammatory rash (whiteheads and blackheads) are improved.
It is usually used to treat acne vulgaris (acne).

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant, possibly pregnant or breastfeeding. Stop using this medicine and consult with your doctor if you become pregnant while using this medicine or want to become pregnant.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, apply an appropriate amount of the medicine to the affected area, once a day between evening and bedtime, after washing your face. Strictly follow the instructions.
  • Use only for acne on your face.
  • Do not apply this medicine on areas with cuts, scratches or eczema.
  • Avoid applying to the eyes, lips, wings of the nose and mucosa.
  • Pay attention so that this medicine does not get in your eyes. If the medicine gets in your eyes, rinse it off with water immediately.
  • If you miss a dose on the day before, apply an appropriate amount of the medicine, as instructed, between evening and bedtime. You should not apply this medicine twice a day or two doses at one time.
  • If you accidentally apply more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop applying this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Avoid excessive exposure to ultraviolet rays, such as sunlight and tanning lamps, while using this medicine.
  • This medicine has bleaching properties. Pay attention not to let it get on your hair or clothes.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include skin irritation, skin pain and allergic dermatitis. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight and moisture. Store at room temperature (1 to 30 degrees Celsius).
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.