くすりのしおり

Internal
Published: 11/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
P-TOL Chewable Tab. 500mg
 Active ingredient:
Sucroferric oxyhydroxide
 Dosage form:
brown tablet, outside diameter: 20.5 mm, internal diameter: 6.0 mm, thickness: about 6.4 mm
 Print on wrapping:
ピートル500, 高リン血症治療剤/食直前に噛み砕いて服用, KISSEI PA 500, 高リン血症治療剤, 食直前に服用

Effects of this medicine

This medicine absorbs phosphorous in the digestive tract and prevents absorption of phosphorous into the body. It therefore decreases blood phosphorous concentration.
It is usually used to improve hyperphosphatemia in the chronic kidney disease patients on dialysis.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, start with 250 mg of iron at a time, 3 times a day immediately before meals. Then the dosage may be adjusted according to the symptoms and blood phosphorous concentration, however, the maximum daily dose is 3,000 mg. This preparation contains 500 mg of the iron in a tablet. Strictly follow the instructions.
  • Chew the medicine in the mouth.
  • If you miss a dose, skip the missed dose and continue your regular dosing schedule without changing the amount of the next dosage. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Your stool may turn black due to components of this medicine.
  • Transient discoloration (brownish-red) of the mouth may occur.
  • If you are instructed to restrict intake of phosphorous-rich food, strictly follow the instructions of the dietary therapy.
  • Serum concentrations of ferritin and hemoglobin may be checked periodically.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include diarrhea. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.