くすりのしおり

Internal
Revised: 5/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Zagallo Capsules 0.5mg
 Active ingredient:
Dutasteride
 Dosage form:
pale red opaque oblong capsule, whole length: approx. 19.3 mm, thickness: approx. 6.6 mm
 Print on wrapping:
(face) ザガーロ0.5mg (back) ZAGALLO 0.5mg, ザガーロ 0.5mg, GS MUF

Effects of this medicine

This medicine inhibits both isoforms (type 1 and type 2) of 5 alpha-reductase, suppresses the conversion of dihydrotestosterone from testosterone and retard the progression of male pattern hair loss.
It is usually used to treat male pattern alopecia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you are planning to undergo prostate cancer screening (PSA test).
    If you have liver dysfunction.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for male adults, take 1 capsule (0.5 mg of the active ingredient) once a day. This medicine may be replaced with a low-dose capsule (0.1 mg of the active ingredient) once a day as needed. Strictly follow the instructions.
  • The ingredients contained in a capsule may irritate the oropharyngeal mucosa. Do not chew or open the capsule when you take this medicine.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Women and children should not touch the contents leaking from the capsule, as it is absorbed through the skin. If the contents get on the skin, wash the area with soap and water immediately.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include erectile dysfunction, libido (sexual desire) decreased, decrease in semen volume and ejaculation failure. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • loss of appetite, general malaise, yellowing of the skin and mucosa [liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture. Keep this medicine in press-through package (PTP) sheets.
  • Discard the remainder. Do not store them. Ask the pharmacy or medical institution on how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.