くすりのしおり

Internal
Published: 9/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Farydak capsules 15mg
 Active ingredient:
Panobinostat lactate
 Dosage form:
orange opaque capsules, major axis: 19.4 mm, minor axis: 6.9 mm
 Print on wrapping:
ファリーダック15mg, FARYDAK15mg, LBH15mg

Effects of this medicine

This medicine inhibits histone deacetylase and is considered to suppress cancer cell growth.
It is usually used to treat recurrent/refractory multiple myeloma.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2 capsules (20 mg of panobinostat) at a time, once a day, 3 doses per week in Weeks 1 and 2 of each 21-day cycle and rest in Week 3 . The dosage should be reduced according to your symptoms. Strictly follow the instructions.
  • If you missed a dose, you can take up to 12 hours after the specified dose time. However, if it already has passed more than 12 hours, skip the missed dose and take the next usual scheduled dose. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Avoid taking the medicine with hypericum perforatum (Saint John's wort)-contained food, since it may weaken the medicinal effects.
  • Avoid driving a car or performing dangerous operations since dizziness, light headedness, or loss of consciousness may occur.
  • If you have a childbearing potential, you and your partner should use birth control while taking this medicine and for a while after the treatment, since fetal toxicity has been reported in an animal study.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include diarrhea, fatigue and anemia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • muddy/watery stool [diarrhea]
  • hyperventilation, conscious disorder, shaking of fingers [symptom of dehydration]
  • anemic symptoms, fever, bleeding tendency [myelosuppression]
  • abdominal pain, vomiting of blood, melena, black stool [bleeding]
  • fever, shortness of breath, tachycardia [infections]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacist and the medical institution how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.