くすりのしおり

Internal
Revised: 12/2016

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
CLOPIDOGREL Tablets 75mg "SANWA"
 Active ingredient:
Clopidogrel sulfate
 Dosage form:
white to faintly yellowish white tablet, diameter: 8.6 mm, thickness: 4.9 mm
 Print on wrapping:
クロピドグレル錠75mg「三和」, クロピドグレル, 75mg, CLOPIDOGREL 75 “SANWA”, クロピドグレル75mg「三和」, 抗血小板剤

Effects of this medicine

This medicine suppresses platelet aggregation attributed to platelet activation and consequently prevents thrombus formation in blood vessels.
It is usually used for the suppression of recurrence of ischemic cerebrovascular disorder (excluding cardiogenic embolism) after its event, for the treatment of acute coronary syndrome, stable angina pectoris and old myocardial infarction in patients who are candidates for percutaneous coronary intervention (PCI), and for the suppression of thrombus formation and embolization in peripheral arterial disease.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you are bleeding or scheduled for tooth extraction or surgery.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For suppression of recurrence of ischemic cerebrovascular disorder (excluding cardiogenic embolism) after its event: In general, for adults, take 1 tablet (75 mg of clopidogrel) at a time, once a day. You may be instructed to take 50 mg at a time, once a day according to the age, body weight or symptoms.
    For acute coronary syndrome, stable angina pectoris and old myocardial infarction in patients who are candidates for percutaneous coronary intervention (PCI): In general, for adults, take 4 tablets (300 mg of clopidogrel) at a time, once a day on the first day of the administration, then take 1 tablet (75 mg) at a time, once a day as the maintenance dose.
    For suppression of thrombus formation and embolization in peripheral arterial disease: In general, for adults, take 1 tablet (75 mg of clopidogrel) at a time, once a day.
    This preparation contains 75 mg of clopidogrel in a tablet. In any case, strictly follow the instructions.
  • Avoid taking this medicine on an empty stomach.
  • If you miss a dose, take a dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include bleeding, jaundice, nausea/vomiting and loss of appetite. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • sudden intense headache, nausea/vomiting, hemiplegia of face or limbs [intracranial bleeding]
  • melena (black stool, bloody stool), vomiting of blood, vision disorder, joint pain [gastrointestinal bleeding, ocular fundus bleeding, joint hematoma]
  • general malaise, nausea, yellowing of the skin and the conjunctiva [liver dysfunction, jaundice]
  • general malaise, purpura (bruise of the skin), loss of appetite [thrombotic thrombocytopenic purpura]
  • sore throat, fever (hyperthermia), nasal bleeding/gum bleeding/subcutaneous bleeding [thrombocytopenia, agranulocytosis, pancytopenia including aplastic anemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.