くすりのしおり

Internal
Revised: 7/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Akineton Fine Granule 1%
 Active ingredient:
Biperiden hydrochloride
 Dosage form:
white fine granule
 Print on wrapping:

Effects of this medicine

This medicine improves tremor in hands, muscle stiffness and slow movement by acting on the central nervous system.
It is usually used to treat Parkinson's disease symptoms.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have glaucoma or myasthenia gravis.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, start by taking 0.1g (1 mg of the active ingredient) at a time, twice a day. The dosage may be gradually increased up to 0.3 to 0.6 g (3 to 6 mg of the active ingredient) in divided doses a day. However, the dosage may be adjusted according to your age or symptoms. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Avoid performing dangerous operations such as driving a car, as this medicine causes sleepiness, accommodation disorders or decrease of attention/concentration/reflex movement.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash and hepatic disorder (general malaise, loss of appetite and nausea). If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • acute fever, muscle stiffness, tremor in limbs  [malignant syndrome]
  • unable to stop using this medicine and becoming dependent on it  [dependence]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.