くすりのしおり

Internal
Revised: 5/2016

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Sunvepra Capsule 100mg
 Active ingredient:
Asunaprevir
 Dosage form:
white to faint yellow oval soft capsule, diameter major axes:14.9mm, diameter minor axes: 9.3 mm
 Print on wrapping:
スンベプラカプセル100mg,BMS711,1日2回服用,Sunvepra,100mg

Effects of this medicine

This medicine inhibits protease involved in hepatitis C virus replication, and shows suppression effects on the proliferation of hepatitis C virus (antiviral effects). This medicine is used concomitantly with daclatasvir.
It is usually used to treat chronic hepatitis C and compensated cirrhosis type C.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have liver dysfunction.
    If you have hepatitis B virus (HBV) infection or have had HBV infection.
  • If you are pregnant, possibly pregnant (referred to the precaution of concomitant medicine, daclatasvir) or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 capsule (100 mg as asnaprevir) at a time, twice a day. It is used concomitantly with daclatasvir, and duration of medication is 24 weeks. Strictly follow the instructions.
  • If you missed a dose, and if you have more than 4 hours interval for the next dose, take the missed dose as soon as possible and continue your regular dosing schedule. If it is less than 4 hours interval for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Avoid taking any food containing St. John's wort, as it may decrease the blood level of the medicine and diminish the effects of this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include headache and fever. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, see your doctor immediately.
  • general malaise, nausea, vomiting loss of appetite , itching, yellow discoloration of the white of eyes/skin/urine [liver dysfunction, hepatic failure]
  • round or oval red rash, fever, joint pain [erythema multiforme]
  • bleeding tendency (nose bleeding, gum bleeding, subcutaneous hemorrhage), bruise [decreased platelet count]
  • fever, dry cough, breathing difficulty [interstitial pneumonia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacy or medical institution how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.