くすりのしおり

Internal
Published: 6/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
GLIBENCLAMIDE Tablets 1.25mg "SANWA"
 Active ingredient:
Glibenclamide
 Dosage form:
white tablet, with a split line, diameter: 6.0 mm, thickness: 1.9 mm
 Print on wrapping:
グリベンクラミド錠1.25mg「三和」, 糖尿病用薬, 1.25, グリベンクラミド1.25, GLIBENCLAMIDE 1.25 “SANWA”, グリベンクラミド1.25「三和」, Sc315

Effects of this medicine

This medicine stimulates pancreatic beta cell, promotes insulin secretion, and consequently lowers blood glucose.
It is usually used for the treatment of non-insulin-dependent diabetes mellitus.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: ketosis, diabetic coma or precoma, insulin-dependent diabetes mellitus, liver dysfunction, kidney dysfunction, infection, injury, gastrointestinal disorder such as diarrhea or vomiting.
    If you are just after/before having surgery.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 to 2 tablets (1.25 to 2.5 mg of the active ingredient), if you are instructed to take once a day, before or after breakfast; if you are instructed to take twice a day in devided dose, before or after breakfast and supper. The dosage may be adjusted as necessary, then the maintenance dose will be determined, however, the maximum daily dose is 8 tablets (10 mg). Strictly follow the instructions.
  • If you miss a dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Share better understanding with your family about your diabetes mellitus.
  • Take meals regularly and avoid overeating and overdrinking.
  • This medicine may cause hypoglycemic symptoms. Pay close attention when you perform dangerous operations such as driving a car, operating machinery or working at heights.
  • If episode of hypoglycemia is occurred, take sugar or glucose. If you take an alpha-glucosidase inhibitor (miglitol, acarbose or voglibose) simultaneously taking the medicine, and episode of hypoglycemia is occurred, take glucose.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, photosensitivity and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • lassitude, severe hunger, sweating [hypoglycemia]
  • sore throat, fever (hyperthermia), muscle pain [agranulocytosis]
  • malaise, shortness of breath, pallor [hemolytic anemia]
  • general malaise, nausea, yellowness in skin or conjunctiva [hepatitis, liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Do not store the remainder and ask your pharmacy or medical institution how to discard it.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.