くすりのしおり

Internal
Revised: 3/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
COVERSYL Tablets 4mg
 Active ingredient:
Perindopril erbumine
 Dosage form:
white to faintly yellowish white tablet, diameter: 7.5 mm, thickness: 2.7 mm
 Print on wrapping:
コバシル 4mg, Coversyl 4mg

Effects of this medicine

By its inhibitory action on angiotensin-converting enzymes, this medicine suppresses production of hypertensive substance angiotensin II, reduces peripheral vascular resistance and consequently lowers blood pressure.
It is usually used to treat hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have a history of angioedema.
    If you are on apheresis (unwanted component removal using adsorption devices) or hemodialysis.
  • If you are pregnant, possibly pregnant, or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1/2 to 1 tablet (2 to 4 mg of the active ingredient) at a time, once daily. The dosage may be adjusted according to the age or symptoms or increased to maximum 2 tablets (8 mg) daily. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness and lightheadedness due to decreased blood pressure. Take care in working at heights, driving a car or operating dangerous machinery.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include cough, abnormal feeling in larynx, rash, eruption, dizziness, headache and nausea. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • swelling of eyelids, lips, tongue or throat; breathing difficulty  [angioedema]
  • decreased urine output, edema, loss of appetite  [acute renal disorder]
  • numbness of limbs or lips, muscular weakness, paralysis in limbs  [hyperkalemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.