くすりのしおり

Internal
Revised: 7/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Careload LA Tablets 60mcg
 Active ingredient:
Beraprost sodium
 Dosage form:
white to yellowish white tablet (diameter:7.0mm, thickness:2.9mm)
 Print on wrapping:
(Face) ケアロード, LA60μg, TR60, house-mark, (Back) ケアロードLA60μg, house-mark

Effects of this medicine

This medicine dilates blood vessels and prevents blood clotting by exerting an action on the prostacyclin receptors on blood vessels and platelets, thus improving the blood flow.
It is usually used in the treatment of pulmonary arterial hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have bleeding due to haemophilia, capillary fragility, upper gastrointestinal ulcer, urinary tract haemorrhage, haemoptysis, ocular fundus haemorrhage, etc.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet (60 mcg of the active ingredient) at a time, twice daily, after breakfast and supper. The dose may be increased slowly while observing your symptoms. When the dose is increased, it may be taken at a maximum dose of 3 tablets (180 mcg) at a time, twice daily, after breakfast and supper. Strictly follow the instructions.
  • This medicine is a sustained-release preparation. Do not split, crush or grind the tablets. Take it without crunching.
  • If you miss a dose, take the missed dose as soon as possible. However, the next dose should be taken about 12 hours apart, and after a meal. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Since this medicine may cause consciousness disorder etc., pay close attention when you operate dangerous machinery such as driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include headache, flushed face, hot flush, queasy, malaise, diarrhoea, palpitations, abdominal pain, bleeding tendency, subcutaneous haemorrhage, nasal bleeding, anaemia, itching, rash, eczema, erythema and hives. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • headache, queasy, visual impairment  [cerebral haemorrhage, digestive tract haemorrhage, pulmonary haemorrhage, ocular fundus bleeding]
  • facial pallor, cold sweat, dizziness on standing up, loss of consciousness [shock, syncope, loss of consciousness]
  • fever, dry cough, breathing difficulty [interstitial pneumonia]
  • general malaise, loss of appetite, yellowing of the skin and the whites of the eyes  [hepatic function disorder]
  • feeling of chest pressure, chest pain with a strangled feeling, cold sweat  [angina, myocardial infarction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of infants and children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Consult with your dispensing pharmacy or medical facility when you discard the medicine.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.