くすりのしおり

Internal
Revised: 8/2010

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
OZEX TAB. 150
 Active ingredient:
Tosufloxacin tosilate hydrate
 Dosage form:
white tablet, φ: 8.6 mm, thickness: 4.7 mm
 Print on wrapping:

Effects of this medicine

This medicine is new quinolone antimicrobials to inhibit DNA replication of bacteria and shows antibacterial action.
It is usually used in the treatment of wide-range infections such as respiratory infections, urinary tract infections, otological infections, etc.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
    If you are a patient with convulsive disease such as epilepsy, or have a history of convulsive disease.
    If you are a patient with renal dysfunction.
    If you are a patient with myasthenia gravis.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • General dosage regimen: For adults, take 2-3 tablets (300-450 mg of the active ingredient) in 2 or 3 divided doses, daily. The dosage should be adjusted according to the disease, age or symptoms. If symptoms are severe or if the dose seems to be insufficient, the dose is increased up to 4 tablets (600 mg) daily. Strictly follow the instructions of your doctor/pharmacist.
    For osteomyelitis, arthritis
    , for adults, take 1 tablet (150 mg of the active ingredient) at a time, 3 times a day. The dosage should be adjusted according to the disease, age or symptoms. If symptoms are severe or if the dose seems to be insufficient, the dose is increased up to 4 tablets (600 mg) daily. Strictly follow the instructions of your doctor/pharmacist.
    For typhoid, paratyphoid
    , for adults, take 1 tablet (150 mg of the active ingredient) at a time, 4 times a day, for 14 days. Strictly follow the instructions of your doctor/pharmacist.
  • Take a dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT take double doses to make up for the missed dose.
  • If you took too much of the medicine (more than ordered), check with your doctor/pharmacist.
  • Do not stop taking the medicine without the instructions of your doctor.

Precautions while taking this medicine

Possible adverse reactions to this medicine

Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: rash, discomfort in stomach, abdominal discomfort, diarrhea/loose stool, etc.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • breathing difficulty, swelling around eyes or lips, redness  [shock, anaphylactoid symptoms]
  • redness in the skin, blister, bulbar conjunctival congestion  [toxic epidermal necrosis, Stevens-Johnson syndrome]
  • general malaise, loss of appetite, yellowing in the skin or conjunctiva  [hepatic dysfunction, jaundice]
  • abdominal pain, diarrhea, melena  [pseudomembranous colitis, hemorrhagic colitis]
  • muscular pain in limbs, weakness, reddish brown urine  [rhabdomyolysis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat, moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.