くすりのしおり

Internal
Revised: 11/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Clarith tab. 200 [for Helicobacter pylori Infection]
 Active ingredient:
Clarithromycin
 Dosage form:
white tablet (φ: 8.6 mm, thickness: 5.4 mm)
 Print on wrapping:

Effects of this medicine

This medicine is macrolide antibiotics, inhibits protein synthesis of bacteria to suppress bacterial growth, and shows antibacterial action.
It is usually used for eradication of Helicobacter pylori infection in gastric and duodenal ulcers, and Helicobacter pylori-associated gastritis.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: hepatic disorder, renal disorder, cardiac disease or hypokalemia.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Combined use of Clarith, amoxicillin hydrate and lansoprazole: In general, for adults, take 1 tablet (200 mg of the active ingredient [titer]), 750 mg of amoxicillin hydrate (titer) and 30 mg of lansoprazole, all at one time, twice daily, for 7 days.
    Combined use of Clarith, amoxicillin hydrate and omeprazole
    : In general, for adults, take 1 tablet (200 mg of the active ingredient [titer]), 750 mg of amoxicillin hydrate (titer) and 20 mg of omeprazole, all at one time, twice daily, for 7 days.
    Combined use of Clarith, amoxicillin hydrate and rabeprazole sodium
    : In general, for adults, take 1 tablet (200 mg of the active ingredient [titer]), 750 mg of amoxicillin hydrate (titer) and 10 mg of rabeprazole sodium, all at one time, twice daily, for 7 days.
    Combined use of Clarith, amoxicillin hydrate and esomeprazole: In general, for adults, take 1 tablet (200 mg of the active ingredient [titer]), 750 mg of amoxicillin hydrate (titer) and 20 mg of esomeprazole, all at one time, twice daily, for 7 days.
    The dosage of this medicine may be increased according to symptoms in any case, however, the dosage is limited to 2 tablets (400 mg [titer]) at a time, twice daily. Strictly follow the instructions of your doctor and pharmacist.
  • If you miss a dose, take the missed dose as soon as possible when you remember that you missed a dose. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include loose stool, diarrhea, taste abnormality, rash and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • breathing difficulty, convulsion, systemic redness accompanied by itching  [shock, anaphylaxis]
  • general malaise, loss of appetite, yellowing in the skin or conjunctiva  [fulminant hepatitis, hepatic dysfunction, jaundice, hepatic failure]
  • general malaise, headache, nasal bleeding, gum bleeding  [thrombocytopenia, pancytopenia, hemolytic anemia, leukocytopenia, agranulocytosis]
  • redness in the skin, blister, bulbar conjunctival congestion  [toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiform]
  • abdominal pain, diarrhea, melena  [pseudomembranous colitis, hemorrhagic enterocolitis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep the medicine out of the reach of children. Store it away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.