くすりのしおり

Internal
Published: 3/2008

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
EBRANTIL Capsules 30mg
 Active ingredient:
Urapidil
 Dosage form:
white capsule (major axis: 14.6 mm, minor axis: 5.3 mm)
 Print on wrapping:
EBRANTILcap.30mg, エブランチルカプセル30, 30mg, KC154

Effects of this medicine

This medicine dilates peripheral vessels and lowers blood pressure by its antagonistic action on alpha-1 receptors. Also, it makes urinating easier by suppressing smooth muscle contraction in the prostate and the urethra, and dilating the urethra.
It is usually used to treat hypertension, and dysuria associated with prostatic hyperplasia and neurogenic bladder.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you ever experienced any allergic reaction (itch, rash, etc.) to any medicine.
    If you are a patient with liver disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • General dosage regimen:
    Treatment of essential hypertension, renal hypertension, hypertension associated with pheochromocytoma
    , for adults, the initial dose is started with 15 mg of the active ingredient at a time, twice daily, and if the effect is insufficient, the dose will be gradually increased at 1-2 week intervals up to 60 mg at a time, twice daily, after breakfast and supper. The dosage may be adjusted according to the age or symptoms.
    Treatment of dysuria associated with prostatic hyperplasia
    , for adults, the initial dose is started with 15 mg of the active ingredient at a time, twice daily, and if the effect is insufficient, the dose will be gradually increased at 1-2 week intervals up to 30-45 mg at a time, twice daily, after breakfast and supper. The dosage may be adjusted according to the symptoms, however, the maximum daily dosage is 90 mg.
    Treatment of dysuria associated with neurogenic bladder
    , for adults, the initial dose is started with 15 mg of the active ingredient at a time, twice daily, and the dose will be gradually increased at 1-2 week intervals up to 30 mg at a time, twice daily, after breakfast and supper. The dosage may be adjusted according to the age or symptoms, however, the maximum daily dosage is 90 mg. This preparation contains 30 mg of the active ingredient in a capsule. Strictly follow the instructions of your doctor/pharmacist.
  • Take a dose as soon as possible when you remembered that you missed a dose. However, it is needed to take an interval of 4-5 hours before the next dose. If it is 2-3 hours or less before the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT take double doses to make up for the missed dose.
  • If you took too much of this medicine (more than ordered), check with your doctor/pharmacist.
  • Do not stop taking this medicine without the instructions of your doctor.

Precautions while taking this medicine

  • You may feel dizziness/stagger due to decreased blood pressure. Do not drive a car, work at heights, or operate dangerous machinery while taking this medicine.

Possible adverse reactions to this medicine

Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: headache, headache dull, dizziness, nausea, vomiting, lightheadedness, stagger, rash, etc.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • General malaise, vomiting, yellowness in skin or conjunctiva [liver dysfunction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep the medicine out of the reach of children. Store it away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.