くすりのしおり

Internal
Revised: 4/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
AVAPRO Tablets 50mg
 Active ingredient:
Irbesartan
 Dosage form:
white to yellowish white tablet (major axis: 8.5 mm, minor axis: 4.4 mm, thickness: 3.1 mm)
 Print on wrapping:
アバプロ, 50mg, DS512

Effects of this medicine

This medicine is a competitive antagonist for angiotensin II type 1 receptors, and decreases blood pressure.
It is usually used to treat hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you are a patient with diabetes mellitus.
  • If you are pregnant, breastfeeding or possibly pregnant.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 to 2 tablets (50 to 100 mg of the active ingredient) at a time, once daily. The dosage may be adjusted according to the diseases, age or symptoms, however, the maximum daily dose is limited to 4 tablets (200 mg). Strictly follow the instructions.
  • If you miss a dose, take as soon as possible. However, it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • The medicine may cause dizziness or lightheadedness since the blood pressure is decreased. Pay attention when you work at heights, drive a car or operate dangerous machinery.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include dizziness, cough, headache, rash, urticaria and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • breathing difficulty, swelling of face, tongue or throat [angioedema]
  • weakness of the limbs, numbness of lips, muscle weakness [hyperkalemia]
  • vomiting, faint, loss of consciousness [shock, syncope, unconsciousness]
  • swelling, general malaise, decreased urine output, anuria [renal failure]
  • general malaise, vomiting, yellowing of the skin and the white of eyes [hepatic function disorder, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store it at room temperature ranging 1 to 30 degrees Celsius, away from direct sunlight and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.