くすりのしおり

Internal
Revised: 12/2008

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Acardi capsules 1.25
 Active ingredient:
Pimobendan
 Dosage form:
brownish yellow opaque capsule (length: 16mm, diameter: 6mm)
 Print on wrapping:
(Face) Acardi 1.25mg, 201, (Back) アカルディ1.25mg, company logo, Boehringer Ingelheim, recycle mark

Effects of this medicine

By increasing the calcium ion sensitivity to protein regulating myocardial contraction and also by inhibiting phosphodiesterase (PDE-III) activity, this medicine dilates the blood vessels and improves the symptoms of heart failure such as shortness of breath and difficulty in breathing.
Usually, this medicine is used to treat acute heart failure and chronic heart failure (mild to moderate in severity).

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have ever had any unusual or allergic reaction (itch, rash etc.) to any medicines.
    If you have a heart disorder (myocardial infarction, arrhythmia, etc.).
    If you have a cerebrovascula, hepatic or renal disorder.
  • If you are already pregnant or are breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Acute heart failure: usually for adults, two capsules (2.5 mg of pimobendan) are orally administered once daily, but can be administered twice daily according to the patient's condition. As necessary, this medicine may be administered in combination with other medicines such as digitalis.
    Chronic heart failure (mild to moderate in severity)
    : usually for adults, two capsules (2.5 mg of pimobendan) are orally administered twice daily after meals. The dosage may be adjusted according to the patient's age and symptoms. This medicine is administered in combination with other medicines such as digitalis and diuretics. Follow your doctor's instructions.
  • If you are ordered to take this medicine on regular schedule and you missed a dose, take as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT take a double dose to make up for the missed dose.
  • If you took too much of this medicine, check with your doctor/pharmacist immediately.
  • Do not stop taking this medicine without the instructions of your doctor.

Precautions while taking this medicine

Possible adverse reactions to this medicine

Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: heart pounding, nausea, ventricular extrasystole (abnormal pulse), hypotension, rash, anemia, fatigue.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • dizziness, heart pounding, chest pain, chest discomfort [ventricular fibrillation]
  • heart pounding, shortness of breath, chest disconfort [ventricular tachycardia, ventricular extrasystole]
  • generalized fatigue, loss of appetite, yellowness of the skin or conjunctiva [hepatic dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from heat, moisture and direct sunlight.
  • Discard unused medicine.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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