くすりのしおり

Internal
Revised: 7/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Propitan Powder 10%
 Active ingredient:
Pipamperone hydrochloride
 Dosage form:
white powder
 Print on wrapping:

Effects of this medicine

This medicine blocks the dopamine D2 receptors in the brain dopaminergic systems and alleviates the symptoms such as hallucinations or delusions.
It is usually used for treatment of schizophrenia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rach, etc.) to any medicines.
    If you have heart failure, Parkinson's disease or epilepsy.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 0.5 to 1.5 g powder (50 to 150 mg as the active ingredient) per day for the first 1 to 2 weeks, and then the daily dosage is increased gradually to 1.5 to 6 g powder (150 to 600mg) per day in 3 divided doses, to be adjusted depending on severity of symptoms or age. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause drowsiness, attention deficit or loss of concentration/reflexes. Avoid operating a motor vehicle or machinery.
  • Do not take any alcoholic beverages while taking this medicine, because alcohol may potentiate the effect of this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include photosensitivity, rash, itchiness, decrease in blood pressure, Parkinson's syndrome (finger trembling, etc.), akathisia (temporary inability to sit still), impatience, insomnia and malaise. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • high fever, muscle stiffness, disturbance of consciousness [malignant syndrome]
  • nausea, vomiting, abdominal distention, constipation [intestinal paralysis]
  • sore throat, headache, muscle pain, high fever with chills/tremor  [agranulocytosis, leukopenia]
  • shortness of breath, chest pain [pulmonary embolism]
  • pain in limbs, swollen limbs [deep vein thrombosis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep this medicine out of the reach of children and store away from direct sunlight, heat and moisture.
  • If you have leftover medicines, dispose of them appropriately and do not keep any unused medicine.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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