くすりのしおり

Internal
Revised: 8/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
CODEIN PHOSPHATE POWDER 1% "DAIICHI SANKYO"
 Active ingredient:
Codeine phosphate hydrate
 Dosage form:
white to yellowish white powder
 Print on wrapping:

Effects of this medicine

This medicine suppresses cough by acting directly on cough center of medulla oblongata to suppress cough reflex, and binds to opioid receptor to exert analgesic action and suppresses intestinal peristalsis to suppress diarrhea.
It is usually used for antitussive and sedative in various respiratory diseases, analgesic in pain, and improvement of severe diarrhea symptoms.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: respiratory depression, bronchial asthma attack, liver dysfunction, heart failure secondary to chronic lung disease, convulsive conditions, acute alcoholism, hemorrhagic colitis, hypersensitivity to opiate alkaloid, or bacterial diarrhea.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2 g (20 mg of the active ingredient) at a time, 6 g (60 mg) daily. The dosage may be adjusted according to the age or symptoms. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as possible. However, if it is almost for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause sleepiness / dizziness. Avoid operating dangerous machinery, such as driving a car.
  • Pay attention that alcohol may intensify medical effects, resulting in respiratory depression, hypotension, marked sedation or coma.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • unable to stop taking the medicine and dependent on it [drug dependence]
  • breathing becomes shallow and rapid, breathing difficulty [respiratory depression]
  • difficulty in thinking, unable to recognize time or place, seeing things or hearing sounds that do not really exist [confusion, delirium]
  • chest pain, breathing difficulty, bluish nails on the limbs, bluish lips, episodic shortness of breath, wheezing (whistling breath), stuffy throat [atelectasis, bronchospasm, laryngeal edema]
  • abdominal bloating, constipation, abdominal pain, nausea/vomiting [paralytic ileus, toxic megacolon]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. If you dispose of unused medicines, ask the pharmacy or the medical institution about proper disposal of them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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