くすりのしおり

Internal
Published: 4/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
MINNEBRO TABLETS 5mg
 Active ingredient:
Esaxerenone
 Dosage form:
faintly reddish white tablet, diameter: 8.1 mm, thickness: ca. 4.1 mm
 Print on wrapping:
ミネブロ5mg, DSC366

Effects of this medicine

This medicine exerts a selective binding of mineralocorticoid receptor and inhibits activation of mineralocorticoid receptor by aldosterone in order to control blood pressure.
It is usually used to treat hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions ( itch, rash, etc. ) to any medicines.
    If you have: hyperkalemia or renal dysfunction.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2.5 mg of the active ingredient at a time, once a day. The dose can be increased up to 5 mg a day. However, you need to start with 1.25 mg daily based on your renal function, etc. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • With your blood pressure dropping, you may feel dizzy/lightheaded. Pay attention when you work at heights or operate dangerous machinery such as driving a car while you take this medicine.
  • Avoid taking any food containing St. John's wort, since it may diminish medicinal effects.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include anemia, dizziness and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • numbness in the limbs/lips, muscular weakness, paralysis of limbs [hyperkalemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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