くすりのしおり

Injection
Published: 2/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
TRASTUZUMAB BS FOR INTRAVENOUS DRIP INFUSIONS 150mg "DAIICHI SANKYO"
 Active ingredient:
Trastuzumab(Genetical Recombination) [Trastuzumab biosimilar 2]
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine suppresses growth of cancer cells by selectively suppressing the action of protein named HER2 necessary for growth of cancer cells.
It is usually used to treat breast cancer overexpressing HER2 and advanced or recurrent gastric cancer overexpressing HER2, not amenable to curative resection.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have or have experienced heart disease.
    If you have been previously diagnosed with high blood pressure or hypertension.
    If you are having difficulty breathing even at rest or have previously experienced such symptom.
    If you are treated with radiation therapy.
    If you have been previously treated with anthracycline medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For breast cancer: In general, administer by intravenous infusion once a day at an interval of once every week.
    For advanced or recurrent gastric cancer, not amenable to curative resection: In general, administered by intravenous infusion once a day at an interval of every three weeks.
  • Dosage and treatment interval depend on the result from checking on the patient's conditions.

Precautions while taking this medicine

  • Since serious cardiac disorder such as cardiac failure may occur, your cardiac function may be checked by echocardiography.
  • If you have a possibility of pregnancy, avoid pregnancy while you are taking this medicine. Also avoid pregnancy for at least seven months after you discontinue this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include fever, vomiting, chill, malaise, asthenia, nausea, pain, headache, fatigue, nail disorder, loss of appetite, diarrhea, stomatitis, hiccup, constipation, anemia and arthralgia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever, general malaise, dizziness on standing up, dizziness, edema, easy breathing in upright position, breathlessness, shortness of breath, chest pain, pounding heart, palpitation, irregular heartbeat, slow pulse, nausea, vomiting, loss of appetite, impaired judgment/mind, decreased/confused consciousness, loss of consciousness [cardiac disorder]
  • cold sweat, dizziness, pale face, general malaise, lightheadedness, decreased consciousness, glow, swelling around the eye and lips, hoarseness, breathing difficulty, shortness of breath, palpitation, hive [shock, anaphylaxis]
  • chills, fever, cough, phlegm, breathing difficulty, shortness of breath, rapid breathing with difficulty, pale lips, pale nails on limbs [interstitial pneumonia, pulmonary disorder]
  • fever, sore throat, nose bleeding, gum bleeding, subcutaneous bleeding, bruise, continuous bleeding, general malaise, dizziness, headache, tinnitus, palpitation, shortness of breath, chills [leukopenia, neutropenia, thrombopenia, anemia]
  • general malaise, itch, nausea, vomiting, loss of appetite, yellowing of white of the eyes and/or the skin, dark urine, epigastralgia, get tired easily, weakness, abdominal fullness, rapid weight gain, hematemesis, fecal occult blood (bright to dark red or black), decreased consciousness [liver failure, jaundice, hepatitis, liver dysfunction]
  • edema, decreased urinary volume, general malaise, hypertension [renal disorder]
  • loss of consciousness, dizziness, decreased/confused consciousness, headache, vomiting, paralysis on one side of the body, difficulty talking, decreased visual acuity, deep breathing, tremor of the limbs [coma, cerebrovascular disease, brain edema]
  • fever, chills, tachycardia, general malaise [sepsis]
  • decreased urine output, decreased consciousness, loss of consciousness, difficulty breathing, vomiting, numbness, weakness [tumor lysis syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

Keywords Search

 

 

 

 

Advanced Search

Browse by drug name A-Z
Browse by drug name A-Z