くすりのしおり

Internal
Published: 6/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
BENIDIPINE HYDROCHLORIDE Tablets 2 "MEEK"
 Active ingredient:
Benidipine hydrochloride
 Dosage form:
yellow tablet, diameter: approx. 6.1 mm, thickness: approx. 2.7 mm
 Print on wrapping:
(face)塩酸ベニジピン, 2「MEEK」, MK18, 2mg, 塩酸ベニジピン「MEEK」
(reverse side)BENIDIPINE HYDROCHLORIDE 2「MEEK」, 塩酸ベニジピン「MEEK」, 2mg, Ca拮抗剤

Effects of this medicine

When calcium flows into cells in vessels, the vessels constrict and the blood pressure increases. This medicine blocks calcium inflow and consequently dilates constricted vessels to decrease blood pressure.
It also dilates vessels of the heart to prevent developing anginal attacks (chest pain which mostly occurs in the heart).
It is usually used in the treatment of hypertension, renal parenchymal hypertension and angina pectoris.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have cardiac disease, hepatic disorder or hypotension.
  • If you are pregnant, breastfeeding or possibly pregnant.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For hypertension and renal parenchymal hypertension: In general, for adults, take 1 to 2 tablets (2 to 4 mg of the active ingredient) at a time, once daily, after breakfast. The dosage may be adjusted according to age or symptoms, however, if the effect is insufficient, it may be increased up to 4 tablets (8 mg) once daily. In severe hypertension, take 2 to 4 tablets (4 to 8 mg) at a time, once daily, after breakfast.
    For angina pectoris
    : In general, for adults, take 2 tablets (4 mg of the active ingredient) at a time, twice daily, after breakfast and supper. The dosage may be adjusted according to age or symptoms.
    Strictly follow the instructions in any case.
  • If you miss a dose, take a dose as soon as possible. After taking the medicine, wait about 8 hours for hypertension, and about 5 hours for angina pectoris to take the next dose. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • The medicine may cause dizziness and lightheadedness due to blood pressure decreased. Be careful when you work at heights, drive a car or operate dangerous machinery.
  • Grapefruit juice may intensify the therapeutic effects of the medicine. Do not take the medicine with grapefruit juice.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include palpitation, facial flush, headache, hypersensitivity (rash, itch, photosensitivity) and gynecomastia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • general malaise, loss of appetite, nausea, yellowing in skin and white of eyes  [hepatic dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard the remainder.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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