くすりのしおり

Injection
Published: 10/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
BACTRAMIN Injection
 Active ingredient:
Trimethoprim
Sulfamethoxazole
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine contains 2 kinds of active ingredients; one is for blocking folate biosynthesis and another is for blocking folate activation. Consequently, it shows synergistic inhibitory effect on the growth of Pneumocystis carinii.
It is usually used to treat carinii pneumonia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have/had blood disease.
    If you or any of your parents or siblings have previously experienced any allergic reactions such as bronchial asthma, rash, and hives.
    If you have: hepatic/renal disorder, folate deprivation or folate metabolism abnormality (a history of gastric resection, just after delivery, congenital folate metabolism abnormality), glucose-6-phosphate dehydrogenase deficiency.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, this medicine is given 3 times daily by intravenous drip infusion over 1 to 2 hours.
  • The treatment period with this medicine depends on your response to the treatment.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include bulla, hives, photosensitivity, rash, erythema, pruritus, bloody stool, convulsion, depression, feeling irritated, headache, drowsiness, light-headed feeling, numbness, tremor, losing strength, malaise, dizziness and hallucination. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • palpitation, shortness of breath, bruise, dizziness [aplastic anemia, hemolytic anemia, anemia megaloblastic, methemoglobinemia, pancytopenia, agranulocytosis, thrombocytopenia]
  • subcutaneous bleeding, bruise, yellowness in the skin and/or the white of the eye, dark urine [thrombotic thrombocytopenic purpura, hemolytic uremic syndrome]
  • breathing difficulty, cold sweat [anaphylaxis, shock]
  • lip/intraoral sore, red spots and breakable blisters (bullas) all over the body [toxic epidermal necrolysis, oculomucocutaneous syndrome]
  • numbness in the limbs, lassitude, muscle pain, red-brown urine [rhabdomyolysis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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