くすりのしおり

External
Published: 12/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
LATACHIMO Combination Ophthalmic Solution"TS"
 Active ingredient:
Latanoprost
Timolol maleate
 Dosage form:
clear and colorless ophthalmic solution, 2.5mL, (bottle) colorless 5mL, (cap) yellow
 Print on wrapping:

Effects of this medicine

This medicine lowers eye pressure by preventing aqueous humor formation and increasing fluid drainage from the eye.
It is usually used to treat glaucoma and ocular hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: bronchial asthma or history of bronchial asthma, bronchospasm, chronic obstructive lung diseases, heart or cardiac failure, sinus bradycardia, atrioventricular block, cardiogenic shock, diabetic ketoacidosis, metabolic acidosis, diabetes mellitus, intraocular inflammation (iritis, uveitis), possibly herpesvirus infection, aphakic eye or pseudophakic eye.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, apply one drop at a time, once a day. Strictly follow the instructions.
  • Wash hands before applying and carefully administer not letting the dropper tip touch the eye.
  • After applying, keep your eyes closed for 1 to 5 minutes, pressing the inner corner of your eyes.
  • Wipe off any excess liquid with a clean wet gauze or tissue.
  • If you need to use other eye drops at the same time, wait more than 5 minutes.
  • If you are wearing contact lenses, take off the lenses and then administer. Wait more than 15 minutes to wear your contact lenses again. (It might lead contact lenses to discoloration).
  • If you miss a dose, apply one drop once if it is within the day. You do not have to administer twice a day nor once for two drops when you noticed to have forgotten administration the next day.
  • If you accidentally apply more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop applying this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Applying the eye-drops may cause iris pigmentation, followed by gradual increase of the symptom. The symptom may stop after withdrawal of the eye-drops, but there may be difference in color tone compared to the other eye without eye-drop treatment. If you become aware of it, consult with your doctor.
  • This medicine may cause transient blurred vision. Avoid driving a car or operating machinery until these symptoms recover.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include eye stimulation, superficial punctate keratitis, conjunctival hyperaemia and keratitis. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • pupil color change [iris pigmentation]
  • foreign-body sensation in the eyes, eye pain, conjunctival hyperaemia [ocular pemphigoid]
  • shortness of breath, breathing difficulty, wheezing (whistling breath) [bronchospasm, respiratory distress, respiratory failure]
  • respiratory distress, loss of consciousness, dizziness on standing up [heart block, heart or cardiac failure, cardiac arrest, cerebral ischemia, cerebrovascular disorders]
  • general malaise, fever, erythema deteriorated by sunlight [systemic lupus erythematosus]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children.
  • Store in refrigerator at 2 to 8℃ before opening.
  • Put in the attached bag and store at room temperature (1 to 30℃) away from light after opening. (It also can be stored in refrigerator.)
  • If you carry it, avoid high temperature conditions such as in a car, and store at dark place such as in a bag.
  • Do not use any medicine that has been stored for more than 4 weeks after opening.
  • Discard the remainder. Do not store them.
  • To avoid improper use and quality loss, do not transfer this solution to any other bottle or container.
  • Do not use any other solution in this bottle.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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