くすりのしおり

Injection
Published: 7/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Diagnogreen for injection 25mg
 Active ingredient:
Indocyanine green
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine is selectively taken up into the liver and excreted into the bile without enterohepatic circulation and renal excretion, and peripheral tissue uptake, after injection. In addition this medicine fluoresces by infrared irradiation.
It is usually used for liver function tests, circulatory function tests, vascular and tissue blood flow evaluation, and identification of sentinel lymph nodes (the first lymph node to which cancer cell is likely to spread from the primary tumor) in patients with breast cancer and malignant melanoma.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have a history of hypersensitivity to iodine.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Liver function tests:
    For determination of plasma elimination and blood retention rates: In general, this medicine is injected intravenously via the cubital vein at the time of the test. For determination of hepatic blood flow: In general, this medicine is injected intravenously at the time of the test.
    Circulatory function tests:
    In general, this medicine is injected intravenously at the time of the test.
    Vascular and tissue blood flow evaluation:
    In general, this medicine is injected intravenously.
    Identification of sentinel lymph nodes in breast cancer and malignant melanoma:
    In general, this medicine is injected subcutaneously or intracutaneously near the cancer.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include shock symptom, nausea, vascular pain, fever/hot feeling, and hives. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • numbness of mouth, nausea, chest distress, bloodshot eyes, edema of eyelids [shock, anaphylaxis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • This medicine may cause shock. You should keep quiet in bed such as lying supine until the completion of the examination after injection.
  • This medicine may affect the thyroid radioactive iodine uptake test. You should receive the test at intervals of one week or more, if necessary.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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