くすりのしおり

Internal
Published: 10/2008

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
CABERGOLINE Tablets 0.25mg "SAWAI" [for Parkinson's disease]
 Active ingredient:
Cabergoline
 Dosage form:
white tablet, diameter: 5.5 mm, thickness: 2.9 mm
 Print on wrapping:
カベルゴリン, 0.25mg「サワイ」, SW-CG.25, 0.25mg

Effects of this medicine

This medicine acts directly on the receptors of neurotransmitters (dopamine) in the brain and shows antiparkinsonian effects to relieve shivering of limbs, muscle stiffness, slowness of movement and gait disturbance.
It is usually used to treat Parkinson's disease.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you have or have a history of a heart valve lesion such as thickening or restricted mobility of heart valve leaflets or stenosis associated with either of these conditions.
    If you have pregnancy toxemia or puerperal hypertension.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, start with 1 tablet (0.25 mg of the active ingredient) at a time, once a day. In the second week, take 2 tablets (0.5 mg) at a time, once a day. The daily dose will then be increased by 2 tablets (0.5 mg) every week under observation to determine the maintenance dose. However, the maximum daily dose is 12 tablets (3 mg). In any case, take the dose once a day, after breakfast. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause sudden onset of sleep without a warning sign (sudden sleep), somnolence (absent-mindedness) and orthostatic hypotension (dizziness on standing up). Avoid performing dangerous operations such as driving a car, operating machinery or working at heights.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, loss of appetite, gastric distress, dry mouth, vomiting, constipation, excitement, light headedness, dizziness, dull headache and dizziness on standing up. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • seeing thing or hearing sound that does not really exist, unfounded assumption, faint, confused consciousness [hallucination, delusion, syncope, delirium, confusion]
  • high fever, consciousness disorder, muscle stiffness [malignant syndrome]
  • fever, dry cough, respiratory distress [interstitial pneumonia]
  • chest pain, edema, respiratory distress [pleurisy, pleural effusion, pleural fibrosis, pulmonary fibrosis, pericarditis, pericardial effusion]
  • shortness of breath, palpitation, edema of legs [heart valve disease]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy on how to discard the remainder.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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