くすりのしおり

Injection
Revised: 2/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
HIBERNA Injection 25mg
 Active ingredient:
Promethazine hydrochloride
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine has anti-cholinergic effects which relieve symptoms of parkinsonism such as muscle stiffness or hand tremor. It also improves allergic symptoms (itching, sneezing, nasal discharge, coughing etc.) by antihistamine effect.
It is usually used to treat paralysis agitans, parkinsonism, sneezing/nasal discharge/coughing caused by upper airway inflammation such as cold, hay fever (pollinosis), allergic rhinitis, itching caused by skin diseases (eczema/dermatitis, cutaneous pruritus, drug eruption, toxicoderma), hives, vasomotor edema and kinesia (motion sickness). It is also used for anesthetic premedication or artificial hibernation by medicine.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you have glaucoma, or obstructive disease in the lower urinary tract such as prostatic hypertrophy.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • This medicine is usually injected subcutaneously or intramuscularly.
  • Treatment duration will be determined depending on the symptoms.

Precautions while taking this medicine

  • This medicine may cause drowsiness. Avoid driving a car or operating dangerous machinery.
  • Pay attention that drinking alcohol may intensify medicinal effects.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include drowsiness, headache, dry mouth, rash, photosensitivity and liver disorder (general malaise, loss of appetite, yellowing of the skin and whites of the eyes). If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever (over 37.5 degrees Celsius), tremor in the limbs, muscle stiffness [neuroleptic malignant syndrome]
  • (when injected to children) loss of consciousness, pauses in breathing during sleeping [infant sleep apnoea attack, etc.]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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