くすりのしおり

Internal
Published: 6/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
MANIDIPINE HYDROCHLORIDE TABLETS 10mg "TOWA"
 Active ingredient:
Manidipine hydrochloride
 Dosage form:
pale yellow tablet with split line, diameter: 7.5 mm, thickness: 3.0 mm
 Print on wrapping:
マニジピン塩酸塩10mg「トーワ」,Manidipine Hydrochloride 10,10mg,Tw004,高血圧の薬

Effects of this medicine

This medicine reduces blood pressure by relaxing and dilating blood vessels through its action on the calcium channel of vascular smooth muscle.
It is usually used to treat hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
    If you have hepatic dysfunction.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 to 2 tablets (10 to 20 mg of the active ingredient) at a time, once a day, after breakfast. However, start taking 1/2 tablets (5 mg) a day and the dosage will then be increased as needed. Strictly follow the instructions of your doctor/pharmacist.
  • If you miss a dose, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. DO NOT take a double dose to make up for the missed dose.
  • If you accidentally take more than your prescribed dose, consult with your doctor/pharmacist.
  • Do not stop taking the medicine uless your doctor instructs you to do so.

Precautions while taking this medicine

  • As dizziness and light-headedness may appear due to lowering of blood pressure, take extra care when working at heights or operating dangerous machinery such as driving a car.
  • Do not take grapefruit juice with this medicine, since some components contained in grapefruit juice may intensify the therapeutic effects of this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itching, photosensitivity, gingival hyperplasia, facial glow, facial flush, palpitation, headache, chylous ascites and gynecomastia.
If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • decreased consciousness, impaired mind/judgement [transient loss of consciousness due to excessive fall of blood pressure]
  • one-sided paralysis of hands/feet and face, numbness, impaired speech/visual disturbance [cerebral infarction]
  • throat pain, purpura, bleeding tendency [agranulocytosis, thrombocytopenia]
  • chest discomfort, palpitation, chest pain [ventricular extrasystoles, supraventricular extrasystoles]
  • generalized red rash, skin exfoliation, fever [erythroderma]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them. If you dispose of unused medicines, ask the pharmacy or the medical institution about proper disposal of drugs.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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