くすりのしおり

Internal
Published: 6/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
MANIDIPINE HYDROCHLORIDE Tablets 10mg "SAWAI"
 Active ingredient:
Manidipine hydrochloride
 Dosage form:
pale yellow tablet, diameter: 7.5 mm, thickness: 3.1 mm
 Print on wrapping:
マニジピン塩酸塩10mg「サワイ」, SW-MD10, Manidipine 10 Hydrochloride「SAWAI」

Effects of this medicine

This medicine blocks the calcium channel to suppress inflow of calcium into cells, leading to expantion of blood vessels and decrease in blood pressure.
It is usually used to treat hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant, breastfeeding or possibly pregnant.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 to 2 tablets (10 to 20 mg of the active ingredient) at a time, once a day after breakfast. However, start taking 0.5 tablets (5 mg) a day and the dosage may be gradually increased as necessary. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness and light headedness due to decreased blood pressure. Pay close attention when working at heights or operating dangerous machinery, such as driving a car.
  • Do not drink grapefruit juice while taking this medicine since it may intensify the medicinal effect.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itch, photosensitivity, gingival hyperplasia, facial flush, heat sensation, palpitation, tachycardia, dizziness, dizziness on standing up, headache, dull headache, nausea, vomiting, loss of appetite, gastric distress, heart burn, abdominal pain, abdominal bloating, constipation, dry mouth, general malaise, lassitude, edema, frequent urination, chylous ascites in renal failure patients and gynecomastia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • dizziness, lassitude, headache, consciousness disorder [transient loss of consciousness due to excessive falloff blood pressure, cerebral infraction]
  • fever, throat pain, bleeding tendency [agranulocytosis, decreased platelets]
  • chest discomfort, palpitation, chest pain [ventricular extrasystoles, supraventricular extrasystoles]
  • generalized red rash, skin exfoliation, fever [erythroderma]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacist and the medical institution how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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