くすりのしおり

Internal
Revised: 9/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
PAROXETINE Tablets 10mg "SAWAI"
 Active ingredient:
Paroxetine hydrochloride hydrate
 Dosage form:
reddish white tablet, diameter: 6.6 mm, thickness: 3.5 mm
 Print on wrapping:
パロキセチン10mg「サワイ」, Paroxetine 10mg

Effects of this medicine

This medicine relieves depressed mood and anxiety by suppressing the reuptake of the neurotransmitter (serotonin) in the brain.
It is usually used to treat depression/depressive state, panic disorder, obsessive-compulsive disorder, social-anxiety disorder and post-traumatic stress disorder.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For depression/depressive state: In general, for adults, take 2 to 4 tablets (20 to 40 mg of paroxetine) at a time, once a day after dinner. Start with 1 to 2 tablets (10 to 20 mg) at a time. As a rule, the dosage will be increased by 1 tablet (10 mg) as a daily dose every week but may be adjusted within the range that does not exceed 4 tablets (40 mg) a day according to your symptoms.
    For panic disorder: In general, for adults, take 3 tablets (30 mg of paroxetine) at a time, once a day after dinner. Start with 1 tablet (10 mg) at a time. As a rule, the dosage will be increased by 1 tablet (10 mg) as a daily dose every week but may be adjusted within the range that does not exceed 3 tablets (30 mg) a day according to your symptoms.
    For obsessive-compulsive disorder: In general, for adults, take 4 tablets (40 mg of paroxetine) at a time, once a day after dinner. Start with 2 tablets (20 mg) at a time. As a rule, the dosage will be increased by 1 tablet (10 mg) as a daily dose every week but may be adjusted within the range that does not exceed 5 tablets (50 mg) a day according to your symptoms.
    For social-anxiety disorder: In general, for adults, take 2 tablets (20 mg of paroxetine) at a time, once a day after dinner. Start with 1 tablet (10 mg) at a time. As a rule, the dosage will be increased by 1 tablet (10 mg) as a daily dose every week but may be adjusted within the range that does not exceed 4 tablets (40 mg) a day according to your symptoms.
    For post-traumatic stress disorder: In general, for adults, take 2 tablets (20 mg of paroxetine) at a time, once a day after dinner. Start with 1 to 2 tablets (10 to 20 mg) at a time. As a rule, the dosage will be increased by 1 tablet (10 mg) as a daily dose every week but may be adjusted within the range that does not exceed 4 tablets (40 mg) a day according to your symptoms.
    In any case, strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so. You must avoid abrupt withdrawal or dose reduction since intolerable symptoms such as dizziness, sweating and nausea may develop.

Precautions while taking this medicine

  • This medicine may cause drowsiness or dizziness. Pay close attention when operating dangerous machinery, such as driving a car.
  • Refrain from taking any food containing St. John's wort (a kind of herb), since it may intensify medicinal effects.
  • Drinking alcohol may intensify medicinal effects. Avoid drinking alcohol while taking this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include malaise, somnolence, dizziness, headache, insomnia, nausea, constipation, loss of appetite, abdominal pain, dry mouth, vomiting, diarrhea, abnormal sexual function (delayed ejaculation, erectile dysfunction, etc.) and sweating. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • anxiety, restlessness, excitement [serotonin syndrome]
  • remaining motionless, muscle stiffness, swallowing difficulty [malignant syndrome]
  • impaired mind, seeing thing or hearing sound that does not really exist, convulsion [confusion, hallucination, delirium, convulsion]
  • fever, redness and swelling of skin/mucosa with rash or blisters, conjunctival hyperemia [toxic epidermal necrolysis, mucocutaneous ocular syndrome, erythema multiforme]
  • loss of appetite, nausea/vomiting, convulsion [syndrome of inappropriate secretion of antidiuretic hormone]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard the remainder.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

Keywords Search

 

 

 

 

Advanced Search

Browse by drug name A-Z
Browse by drug name A-Z