くすりのしおり

Internal
Published: 12/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
RANITIDINE TABLETS 150mg "TSURUHARA"
 Active ingredient:
Ranitidine hydrochloride
 Dosage form:
white to light yellowish white tablets, diameter: 8.7mm, thickness: 4.2mm
 Print on wrapping:
(Face) ラニチジン錠150mg「ツルハラ」, ラニチジン, 150mg, (Back) ラニチジン錠150mg「ツルハラ」, Ranitidine150mg, 150

Effects of this medicine

This medicine has antagonistic actions on the histamine, H2 receptors of gastric mucosa cell and suppresses secretion of gastric fluid or acid and ulcer development. It promotes healing of ulcer.
It is usually used for the treatment of gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger-Ellison syndrome, reflux esophagitis and upper gastrointestinal bleeding, for the improvement of gastric mucosal lesion in acute gastritis and acute exacerbation of chronic gastritis and for anesthetic premedication.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger-Ellison syndrome, reflux esophagitis and upper gastrointestinal bleeding: In general, for adults, take 1 tablet (150 mg of ranitidine) at a time twice a day, after breakfast and before bedtime. However, it is also possible to take 2 tablets (300 mg) once a day before bedtime. The dosage may be adjusted according to the disease, age or symptoms.
    For the improvement of gastric mucosal lesions in acute gastritis and acute exacerbation of chronic gastritis : In general, for adults, take 1 tablet (150 mg of ranitidine) at a time once a day before bedtime. The dosage may be adjusted according to the disease, age or symptoms.
    Anesthetic premedication: In general, for adults, take 1 tablet (150 mg of ranitidine) at a time, 2 times, once before bedtime on the day before surgery and once 2 hours before anesthesia on the day of surgery.
    In any case, strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itch, fever, angioedema (swelling of eyelid, lip or tongue), vasculitis, constipation and diarrhea. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • cold sweat, facial pallor, respiratory distress [shock, anaphylaxis]
  • general malaise/lassitude, internal/submucosal bleeding, fever [aplastic anemia, blood disorder such as pancytopenia]
  • muscle pain, lassitude, reddish brown urine [rhabdomyolysis]
  • general malaise, loss of appetite, yellowing of the skin and the white of the eyes [hepatic dysfunction, jaundice]
  • decreased consciousness/judgement, convulsion, acute involuntary muscular spasm [conscious disorder, convulsion, myoclonus]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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