くすりのしおり

Injection
Revised: 6/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ACICLOVIR INTRAVENOUS INFUSION 250mg "TOWA"
 Active ingredient:
Aciclovir
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine is an antiviral drug that suppresses proliferation of herpes simplex and varicella/herpes zoster viruses through inhibition of viral DNA syntheses.
It is usually used to treat infections caused by herpes simplex and varicella/herpes zoster viruses, and neonatal herpes simplex virus infection.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, children and newborns, inject this medicine by intravenous infusion 3 times a day.
  • This medicine is injected, as a guideline, for about 7 days for adults and children, and for about 10 days for neonatal herpes simplex virus infection. The treatment span may be extended according to symptoms.

Precautions while taking this medicine

  • Please take a larger amount of water than usual while you are on this medicine. However, if you have been instructed to restrict fluid intake, please consult with your doctor or pharmacist.
  • This medicine may cause consciousness disorder. Pay attention when operating dangerous machinery, such as driving a car. Patients with renal dysfunction are more susceptible to consciousness disorder, so avoid operating dangerous machinery if instructed to do so by your doctor.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include fever, rash, erythema, hives, itch, blister, fixed drug eruption, photosensitivity, anemia, nausea, vomiting, abdominal pain, gastric pain, epigastric pain, gastric distress, chest pain, general malaise and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, angioedema, hives [anaphylaxis shock, anaphylaxis (respiratory distress, angioedema, etc.)]
  • high fever, general malaise, bloody urine, subcutaneous bleeding in limbs [pancytopenia, agranulocytosis, decreased platelets, disseminated intravascular coagulation syndrome, thrombocytopenic purpura]
  • decreased urine output, edema of limbs or face, general malaise [acute renal failure]
  • consciousness disorder (coma), delirium, delusion [neuropsychiatric symptom]
  • high fever, bulbar conjunctival hyperemia, erythema [toxic epidermal necrolysis, mucocutaneous ocular syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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