くすりのしおり

Internal
Published: 6/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
GLICLAZIDE TABLETS 40mg "TOWA"
 Active ingredient:
Gliclazide
 Dosage form:
white tablet with split line, diameter: 6.0 mm, thickness: 2.3 mm
 Print on wrapping:
Tw,DG,グリクラジド40 mg, 40 mg

Effects of this medicine

This medicine stimulates pancreatic beta cells and promotes insulin secretion, resulting in decreased levels of blood glucose (sugar in the blood).
It is usually used to treat non-insulin-dependent diabetes mellitus (maturity-onset type diabetes).

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have ketosis (hyperventilation, loss of consciousness, shivering of limbs, etc.), diabetic coma or precoma, insulin-dependent diabetes mellitus, liver or renal dysfunction, infections, external injury or gastrointestinal disorders such as diarrhea/vomiting.
    If you are in the pre-/post-operative period.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, start with 1 tablet (40 mg of the active ingredient) in 1 dose or in 2 divided doses a day, in the morning or in the morning and evening, before or after meal. In general, the maintenance dose is 1 to 3 tablets (40 to 120 mg) a day. However, the maximum daily dose will not exceed 4 tablets (160 mg). Strictly follow the instructions.
  • If you miss a dose, take the missed dose when you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Strictly follow the instructions on dietary/exercise therapy. Skipping or delaying meals, excessive drinking of alcohol, vigorous exercise, diarrhea and vomiting will likely cause hypoglycemia.
  • Hypoglycemic symptoms (such as lassitude, a strong sense of hunger, cold sweat and palpitation) may occur. Pay close attention when working at heights or operating dangerous machinery, such as driving a car.
  • If hypoglycemic symptoms are noted without consciousness disorder, then in general, take sugar. If you take alpha-glucosidase inhibitors (such as acarbose or voglibose) in combination with this medicine, take glucose. If you have decreased consciousness, contact your doctor.
  • Consciousness disorder may occur as a hypoglycemic symptom. Inform your family and persons around you that you are taking this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itching sensation of skin and photosensitivity. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • lassitude, a sense of hunger, sweating [hypoglycemia]
  • headache, sore throat, high fever with chills and shivering [agranulocytosis]
  • general malaise, yellow discoloration of the skin and the white of eyes, loss of appetite [liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard the remainder.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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