くすりのしおり

External
Revised: 8/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
LATACHIMO COMBINATION OPHTHALMIC SOLUTION"SENJU"
 Active ingredient:
Latanoprost
Timolol maleate
 Dosage form:
clear and colorless ophthalmic solution
 Print on wrapping:

Effects of this medicine

This medicine lowers eye pressure by preventing aqueous humor formation and increasing fluid drainage from the eye.
It is usually used in the treatment of glaucoma and ocular hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have:bronchial asthma or history of bronchial asthma, bronchospasm, chronic obstructive lung diseases, heart or cardiac failure, sinus bradycardia, atrioventricular block, cardiogenic shock, diabetic ketoacidosis, metabolic acidosis, diabetes mellitus, intraocular inflammation(iritis, uveitis), possibly herpesvirus infection, aphakic eye or pseudophakic eye.
    If you wear contact lenses.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, apply 1 drop at a time, once daily. Strictly follow the instructions.
  • Do not apply more than once daily since the effect of the medicine to lower intraocular pressure may be diminished if you apply the medicine frequently.
  • Before using, wash your hands with soap and water. Then face up and apply the medicine not to touch the tip of eye dropper to any surface of your eye. After instilling, close your eyes for 1 to 5 minutes, pressing gently on the inner corner of the eye with your finger. The medicine attached around the eye after applying, wipe it off immediately with wet gauze or tissue, or wash the face with the eyes closed. If any leaked and attached medicine remains on the face, it may cause darkening around the eye, or lengthening and thickening of eyelashes. If you need to use other eye drops at the same time, wait more than 5 minutes.
  • Contact lenses may be discolored due to the medicine. Therefore, you are wearing contact lenses, remove the contact lenses before applying the medicine, and wait for at least 15 minutes to wear the contact lenses.
  • If you miss a dose before the end of the day, apply 1 drop immediately. If you noticed it on the next day, do not apply the previous day's dose, and apply 1 drop once a day. You should not use either two drops at one time or twice a day.
  • If you accidentally use more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop using this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Applying the medicine may cause iris pigmentation, followed by gradual increase of the symptom. The symptom may stop after withdrawal of the medicine, but there may be difference in color tone compared to the other eye without eyedrop treatment. If you become aware of it, check with your doctor.
  • Blurred vision may occur temporarily after applying the medicine. Avoid driving a car or operating dangerous machinery until recovering from the symptom.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include eye stimulation, superficial punctate keratitis, conjunctival hyperaemia and keratitis. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • pupil color change [iris pigmentation]
  • abnormal sensation in the eyes, eye pain, conjunctival hyperaemia [ocular pemphigoid]
  • shortness of breath, breathing difficulty, wheezing (whistling breath) [bronchospasm, respiratory distress, respiratory failure]
  • respiratory distress, loss of consciousness, dizziness of standing up [heart block, heart or cardiac failure, cardiac arrest, cerebral ischemia, cerebrovascular disorders]
  • general malaise, fever, erythema deteriorated by sunlight [systemic lupus erythematosus]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • 2.5 mL of the solution is dispensed in a 5-mL container originally.
  • Keep out of the reach of children. Put in the attached light-blocking bag, and store away from direct sunlight.
  • Store at 2 to 8 ℃ before opening.
  • Store at room temperature (1 to 30℃) after opening.
  • Do not use any medicine that has been stored for more than 4 weeks after opening.
  • Discard the remainder. Do not store them.
  • To avoid improper use and quality loss, do not transfer this solution to any other bottle or container.
  • Do not use any other solution in this bottle.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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