くすりのしおり

Injection
Published: 12/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
NAFAMOSTAT MESILATE FOR INJECTION 10mg "TOWA"
 Active ingredient:
Nafamostat mesilate
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine relieves symptoms due to organ damage/bleeding caused by blood clotting. It prevents coagulation in the extracorporeal blood circulation during which the blood is removed from the body to be purified, and then returned to the body.
It is usually used to prevent disseminated intravascular coagulation (DIC) and clotting of perfusing blood in extracorporeal blood circulation.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For disseminated intravascular coagulation (DIC): In general, administer by continuous intravenous injection over a period of 24 hours.
    For prevention of perfusing blood coagulation in extracorporeal blood circulation: In general, the inside of blood circuit is rinsed and filled prior to the start of extracorporeal circulation and then this medicine is continuously injected through an anticoagulant injection line after start of extracorporeal circulation.
  • The treatment span with this medicine is determined based on your symptoms.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, erythema, itch, nausea/vomiting, bleeding tendency, loss of appetite, and general malaise. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • decreased blood pressure, consciousness disorder, respiratory distress [shock, anaphylactoid symptoms]
  • numbness of limbs and lips, muscle weakness, paralysis of limbs [hyperpotassemia]
  • headache, convulsion, consciousness disorder [hyponatremia]
  • nose/gum bleeding, subcutaneous bleeding of limbs [thrombocytopenia]
  • sore throat, high fever, chill [leukopenia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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