くすりのしおり

Internal
Published: 2/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
AMVALO COMBINATION OD TABLETS "TOWA"
 Active ingredient:
Valsartan
Amlodipine besilate
 Dosage form:
pale yellow tablet, diameter: 12.0 mm, thickness: 5.6 mm
 Print on wrapping:
アムバロ配合OD錠「トーワ」, バルサルタン80mg, アムロジピン5mg, Amvalo OD, 高血圧の薬

Effects of this medicine

This medicine blocks the vasoconstrictive effects of angiotensin II produced in the body, and dilates peripheral blood vessel to lower blood pressure in patients with hypertension.
It is usually used to treat hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: diabetes mellitus, renal disorder, hepatic disorder, hyperkalemia or schedule of surgery.
    If you are on dialysis or a regimen of low-salt diet.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet at a time, once a day. Strictly follow the instructions.
  • This medicine is orally disintegrating tablet. Take this medicine in either of the following ways:
    (1)Take this medicine with water or warm water as you do an ordinary tablet.
    (2)Moisten the tablet with saliva on your tongue and crush it lightly with your tongue, then swallow it with saliva. However, never take the tablet without water when you are in a lying position.
  • If you miss a dose, take a dose as soon as possible. However, if it is 8 hours or less before the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • The medicine may cause dizziness or light-headedness since the blood pressure is decreased. Pay attention when you work at heights, drive a car or operate dangerous machinery.
  • Avoid taking the medicine with grapefruit juice, as it may intensify the effect of the medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include dizziness and rash. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • swelling in face/lips/throat/tongue, breathlessness [angioedema]
  • loss of appetite, general malaise, yellowness in skin or conjunctiva [hepatitis fulminant, hepatitis, hepatic function disorder, jaundice]
  • decrease of urine output, edema, loss of appetite [renal failure]
  • loss of consciousness, vomiting, cold feeling [shock, syncope, loss of consciousness]
  • numbness of lips or limbs, muscle weakness, paralysis in limbs [hyperkalemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacy or medical institution how to discard.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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