くすりのしおり

Internal
Published: 2/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
CAMSHIA COMBINATION TABLETS HD "TOWA"
 Active ingredient:
Candesartan cilexetil
Amlodipine besilate
 Dosage form:
light red oval tablets, major axis 8.5 mm, minor axis 5.0 mm, thickness 3.1 mm
 Print on wrapping:
カムシア配合錠HD「トーワ」, カンデサルタンシレキセチル 8mg, アムロジピン 5mg, Camshia HD, 高血圧の薬

Effects of this medicine

This medicine lowers blood pressure by reducing peripheral vascular resistance via antagonism against receptor for the pressor substance angiotensin II as well as via its action upon the calcium channel in the vascular smooth muscle.
It is usually used for treatment of hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have renal disorder, liver disorder, heart failure, hyperkalemia, or hyponatremia.
    If you are on hemodialysis, on low-salt diet therapy or in a preoperative state.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet at a time, once a day. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is less than 8 hours to the next dose, skip the missed dose and then continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • As dizziness and light-headedness may appear due to excessive lowering of blood pressure, take extra care when working at heights or operating dangerous machinery such as driving a car.
  • Do not take the medicine together with grapefruits juice.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itching, photosensitivity, angiitis, dizziness, light-headedness, dizziness on standing up, glow, fall in blood pressure, abdominal discomfort, enlarged feeling of the abdomen, diarrhea, cough, ear ringing, hives and erythema multiforme. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • swelling of face, tongue and throat, breathlessness, feeling cold, vomiting, loss of consciousness [angioedema, shock, syncope, loss of consciousness]
  • decreased urinary output, swelling of face and hands/feet, fever, lassitude, muscle pain, brown urine [acute renal failure, rhabdomyolysis]
  • numbness of hands/feet and lips, muscle weakness [hyperkalemia]
  • yellowing of the skin or whites of the eyes, dullness, loss of appetite [liver dysfunction, jaundice, fulminant hepatitis]
  • fever, sore throat, dullness, nose bleeding, gingival bleeding, subcutaneous bleeding [agranulocytosis, decreased white blood cell count, decreased platelet count]
  • fever, dry cough, breathlessness [interstitial pneumonia]
  • cold sweat, feeling hungry, tremor in hands [hypoglycemia]
  • bradycardia, dizziness [atrioventricular block]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and humidity.
  • Discard the remainder. Do not store them. Ask the pharmacy or medical institution how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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