くすりのしおり

Injection
Revised: 12/2016

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ACICLOVIR for inject by intravenous infusion 250mg "PP"
 Active ingredient:
Aciclovir
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine suppresses the growth of herpes simplex viruses and varicella/herpes zoster viruses by inhibiting DNA synthesis of viruses.
It is usually used to treat infections due to herpes simplex viruses and varicella/herpes zoster viruses and neonatal herpes simplex virus infection.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: renal disorder or liver disorder
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, children and neonates, inject by intravenous infusion more than one hour 3 times a day.
  • This medicine may be injected 7 days for adults and children, 10 days for neonatal herpes simplex virus infection, as a guide. The treatment span may be extended as needed.
  • This medicine may be started in early phase of the disease, because the effect can be expected than near early disease onset.

Precautions while taking this medicine

  • Take appropriate amount of water during administration.
  • This medicine may cause conscious disorder. Pay attention to operating dangerous machinery such as driving a car.
  • Patients with renal dysfunction are more susceptible to conscious disorder, so avoid operating dangerous machinery such as driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include fever, rash, erythema, hives, itch, bulla, fixed drug eruption, photosensitivity, anemia, bloody urine, nausea, consciousness disorder, chest pain, joint pain, general malaise, injection part necrosis and respiratory distress. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, angioedema, palpitation [anaphylactic shock, anaphylaxis]
  • headache, subcutaneous bleeding, sore throat [blood disorder such as pancytopenia, agranulocytosis etc.]
  • decreased urine output, edema, headache [acute renal failure]
  • coma, hallucination, convulsions [neuropsychiatric symptoms]
  • fever, bulbar conjunctival hyperemia, mucosal eruption with pain of oral mucosa etc. [Toxic Epidermal Necrolysis, Stevens-Johnson syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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