くすりのしおり

Internal
Revised: 5/2016

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
VORICONAZOLE TABLETS 50mg "TOWA"
 Active ingredient:
Voriconazole
 Dosage form:
white tablet with split line, diameter: 7.1 mm, thickness: 3.3 mm
 Print on wrapping:
ボリコナゾール50mg「トーワ」,Voriconazole 50,抗真菌剤

Effects of this medicine

This medicine shows the effect against fungal infections in the body, by inhibiting biosynthesis of cell membrane component of fungi (a kind of mold).
It is usually used to treat severe/refractory fungal infections (e.g. aspergillosis, candidiasis, cryptococcosis, etc.).

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: liver dysfunction, arrhythmia or in a condition easy to develop arrhythmia.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For adults (with body weight more than 40 kg): In general, start with 6 tablets (300 mg of the active ingredient) at a time, twice a day on the first day. From the second day on, take 3 or 4 tablets (150 mg or 200 mg) at a time, twice a day between meals. The dosage may be increased according to the diseases, condition or response to the treatment. The maximum dose is 8 tablets (400 mg) at a time, twice a day on the first day and 6 tablets (300 mg) at a time, twice a day after the second day.
    For adults (with body weight less than 40 kg): In general, start with 3 tablets (150 mg of the active ingredient) at a time, twice a day on the first day. From the second day on, take 2 tablets (100 mg) at a time, twice a day between meals. The dosage may be increased up to 3 tablets (150 mg) at a time, twice a day after the second day according to the diseases, condition or response to the treatment.
    In any case, strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause sensitivity to bright light, blurred vision and focus disorder, which may continue after cancelling your medication. Unless you recover from these symptoms during or after cancelling your medication, avoid operating dangerous machinery such as driving a car.
  • Since this medicine may cause photosensitivity (redness appearing on sun-exposed skin), avoid exposure to sunlight by wearing long-sleeved cloths, hat, etc. and exposure to ultraviolet rays by using an effective sunscreen.
  • Avoid taking any food containing St. John's wort (a kind of herb) with this medicine, because the effect of this medicine may be affected.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include photophobia (sensitive to bright light), vision disorder, nausea, vomiting, headache, foggy vision (blurred vision), loss of appetite, insomnia, hallucination, rash and defective color vision. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • cold sweat, paleness of the face, breathing difficulty [shock, anaphylaxis]
  • high fever, skin redness, stomatitis [toxic epidermal necrosis, Stevens-Johnson syndrome, erythema multiforme]
  • general malaise/loss of appetite, yellowing of the skin and the white of eyes, coma [liver disorder]
  • chest pain, palpitation, irregular pulse [electrocardiogram QT prolongation, ventricular tachycardia, ventricular fibrillation, arrhythmia, complete atrioventricular block]
  • general malaise, respiratory distress, general edema [heart failure]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. If you dispose of unused medicines, ask the pharmacist and the medical institution how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

Keywords Search

 

 

 

 

Advanced Search

Browse by drug name A-Z
Browse by drug name A-Z