くすりのしおり

Injection
Published: 2/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
HERBESSER 50 mg for Injection
 Active ingredient:
Diltiazem hydrochloride
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine has calcium antagonistic action to inhibit calcium ion influx of extracellular fluid into cells, and thereby dilates coronary artery and peripheral blood vessels, reduces blood pressure, and slows conduction of impulses in the atrioventricular node, a pathway that the electric energy occurred in the sinoatrial node generating normal sinus rhythm is transmitted from the atria to ventricles.
It is usually used to treat tachyarrhythmia, hypertensive emergency and unstable angina, and for emergency treatment of malignant hypertension during operation.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have hypotension, cardiogenic shock, second-degree or higher atrioventricular (AV) block, sick sinus syndrome (with persistent sinus bradycardia at less than 50 beats/minute, sinus arrest, sinoatrial block, etc.), congestive cardiac failure or cardiomyopathy.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Tachyarrhythmia (supraventricular): In general, for adults, this medicine is given by intravenous injection slowly over approximately 3 minutes.
    Emergency treatment of malignant hypertension during operation: In general, for adults, this medicine is given by intravenous injection slowly over approximately 1 minute. If it is given by intravenous drip infusion, your doctor decides the infusion rate and time monitoring the blood pressure.
    Hypertensive emergency, unstable angina: In general, for adults, this medicine is given by intravenous drip infusion. The infusion rate and time depend on your symptom.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include bradycardia, decreased blood pressure and AV block (skipped pulse beats), If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • slow pulse, general malaise/shortness of breath, dizziness/syncope [complete AV block, severe bradycardia, cardiac arrest]
  • respiratory distress, general edema, fatiguability [congestive cardiac failure]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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