くすりのしおり

Internal
Published: 2/2009

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Wellnara Combination Tablets
 Active ingredient:
Estradiol
Levonorgestrel
 Dosage form:
pale red tablet, diameter: 6 mm, thickness: 2.85 mm
 Print on wrapping:
(face) ウェールナラ配合錠, SC
(back) ウェールナラ配合錠, Wellnara

Effects of this medicine

This medicine suppresses decreasing bone quantity by supplementing estradiol, a type of ovarian hormone. This medicine also contains levonorgestrel, a type of progestational hormone, to protect the endometrium from the actions of ovarian hormones.
It is usually used to treat postmenopausal osteoporosis.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have or are suspected of having estrogen-dependent cancers (breast cancer, cancer of endometrium, etc.).
    If you have a past medical history of breast cancer.
    If you have or have a past medical history of thrombophlebitis, pulmonary embolism or arterial thromboembolic disease (coronary heart disease, stroke, etc.).
    If you have liver disorder or undiagnosed abnormal genital bleeding.
    If you have had a hysterectomy.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take one tablet at a time, once a day. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as you remember. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Avoid taking any food containing St. John's wort, since it may decrease the blood level of the medicine and diminish medicinal effects.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include breast discomfort, breast pain, genital discharge, genital bleeding, abdominal pain and nipple pain. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • leg pain/edema, chest pain, shortness of breath [venous thromboembolism, thrombophlebitis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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