くすりのしおり

Internal
Published: 11/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
MARIZEV Tablets 12.5mg
 Active ingredient:
Omarigliptin
 Dosage form:
yellow, round, film coated tablet, diameter: 5.6 mm, thickness: 3.1 mm
 Print on wrapping:
(表)マリゼブ錠12.5mg, 糖尿病用薬, 週1回1錠のむ, 毎日のむお薬ではありません, □月□日○曜日に1錠のむお薬です, 781, (裏)【飲み忘れた時】・気づいた日に飲む・同じ日に2錠のまない

Effects of this medicine

This medicine inhibits enzyme that degrades incretin, blood glucose stabilizing substance. It consequently enhances insulinotropic action and effect of lowering glucagon level in state of hyperglycemia to improve blood glucose control.
It is usually used to treat type 2 diabetes.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: ketosis, diabetic coma or precoma stage, type 1 diabetes, infection (in case glycemic control by insulin injection is desired), injury, renal dysfunction, pituitary gland disorder, adrenal gland disorder, insufficient diet.
    If you are in pre/postoperative period or debilitated.
    If you exercise intensely or drink a lot of alcohol.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2 tablets (25 mg of the active ingredient) at a time, once a week. If you are a patient with severe or end stage renal dysfunction, take 1 tablet (12.5 mg) at a time, once a week. Strictly follow the instructions.
  • If you miss a dose, take your dose as soon as you remember. Then take your next weekly dose on your regular day. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Strictly follow diet and exercise therapy instructed by your doctor.
  • The medicine may cause hypoglycemic symptoms. Pay attention when you work at heights, drive a car or operate dangerous machinery.
  • In case hypoglycemic symptoms occur, take food or drink that contains enough amount of sugar (sugar, glucose, refreshing drink, etc.). If you are taking the medicine concomitantly with an α-glucosidase inhibitor (medicines which delay absorption of sugar), ingest glucose in case of any hypoglycemic symptoms occur.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include hypoglycemia and constipation. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • chills, craving for food, tremor in limbs [hypoglycemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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