くすりのしおり

Injection
Revised: 7/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Tagamet Injection 200mg
 Active ingredient:
Cimetidine
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine blocks histamine H2 receptor of gastric mucosal barrier cells to suppress gastric acid secretion.
It is usually used for upper gastrointestinal bleeding (due to peptic ulcer, acute stress ulcer or hemorrhagic gastritis), suppression of upper gastrointestinal bleeding due to invasive stress (major surgery requiring postoperative management, cerebrovascular disorder/head injury/multi organ failure/severe burn requiring intensive care) and anesthetic premedication.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For upper gastrointestinal bleeding (due to peptic ulcer, acute stress ulcer or hemorrhagic gastritis): In general, for adults, administer intravenously via slow injection or drip infusion, 4 times a day (every 6 hours). The treatment span depends on your symptoms, however, the normal treatment span is about 7 days.
    For suppression of upper gastrointestinal bleeding due to invasive stress (major surgery requiring postoperative management, cerebrovascular disorder/head injury/multi organ failure/severe burn requiring intensive care): In general, for adults, administer intravenously via slow injection or drip infusion, 4 times a day (every 6 hours). The treatment span depends on your symptoms, however, the normal treatment span is about 3 days for invasive stress due to surgery and about 7 days for other invasive stresses.
    For anesthetic premedication: In general, for adults, administer intramuscularly an hour before anesthesia.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include constipation, rash, gynecomastia, milk secretion, increase of white vaginal discharge, erectile dysfunction and peripheral neuropathy (pain/sensory paralysis/motor disorder of the limbs). If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • cold sweat, facial pallor, breathing difficulty [shock, anaphylactoid symptoms]
  • anemic symptoms, general malaise, sore throat [aplastic anemia, pancytopenia, agranulocytosis, decreased platelets]
  • fever, rash, decreased urine output [interstitial nephritis, acute renal failure]
  • fever, loss of appetite, erythema/blister spreading across a wide area [mucocutaneous ocular syndrome, toxic epidermal necrosis]
  • general malaise, loss of appetite, nausea [liver disorder]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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