くすりのしおり

Internal
Revised: 2/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Triumeq Combination Tablets
 Active ingredient:
Dolutegravir sodium
Abacavir sulfate
Lamivudine
 Dosage form:
purple tablet, major axis: approximately 22 mm, minor axis: approximately 11 mm, thickness: approximately 7.6 mm
 Print on wrapping:

Effects of this medicine

This medicine inhibits integrase of human immunodeficiency virus (HIV) and activities of HIV-1 reverse transcriptase to exert its antiviral effect.
It is usually used to treat HIV infection.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have liver disorder or have previously experienced pancreatitis.
    If you have hepatitis B or C viral infection.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet at a time, once a day, with or without food. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Always carry a Hypersensitivity Reactions Warning Card.
  • This medicine is not for the radical cure of HIV infection. Even if you continue taking this medicine, HIV infection may progress. Tell your doctor about all changes, if any, which have occurred in your physical condition.
  • Pay attention that St. John's wort may decrease the blood level of this medicine.
  • Iron preparations or dietary supplements containing calcium interfere with the absorption of this medicine. If you take iron preparations or dietary supplements containing calcium separately from food, take this medicine either 2 hours before or 6 hours after taking them.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, insomnia, headache, dizziness, fatigue and diarrhea. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever, diarrhea, skin eruption [hypersensitivity]
  • rash, fever, swollen lymph node [drug-induced hypersensitivity syndrome]
  • fever, eye bloodshot, facial swelling [toxic epidermal necrolysis, muco-cutaneo-ocular syndrome, erythema multiforme]
  • persistent fever, bleeding tendency, prolonged bleeding [serious blood disorder]
  • severe upper abdominal pain, lumbar/back pain, fever [pancreatitis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Seek advice of your pharmacy or medical institution about proper disposal of the unused medicines.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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