くすりのしおり

Injection
Revised: 9/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ESPO SUBCUTANEOUS INJECTION 24000 SYRINGE [autologous blood donation]
 Active ingredient:
Epoetin alfa(genetical recombination)
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine acts on cells that grow into red blood cells (RBCs) to increase the number of RBCs.
It is usually used for autologous blood donation (donation of own blood before surgery in a patient for whom blood transfusion is necessary, because a certain amount of bleeding is expected by surgery).

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have experienced myocardial infarction, lung infarction, cerebral infarction, etc.
    If you have hypertension.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, inject subcutaneously once a week.
  • The duration of administration depends on the blood collection volume and the severity of anemia. Ask your doctor about your dosing schedule.
  • If you use this medicine for the first time or after an interval, you may be administered lower dose subcutaneously and observed whether any abnormalities occur.

Precautions while taking this medicine

  • You need to take iron to get an adequate efficacy. If you are prescribed iron preparation, you should take it as instructed by your doctor.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include increased blood pressure. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • paralysis of face and limbs on one side, numbness, language disorder such as inarticulateness [cerebral infarction]
  • headache, dizziness, nausea [cerebral hemorrhage]
  • general malaise, loss of appetite, yellowing in skin and white of eyes [hepatic function disorder, jaundice]
  • headache, disturbed consciousness, convulsion [hypertensive encephalopathy]
  • hives, dyspnea, lip edema, pharyngeal edema (swelling of lips or throat) [shock, anaphylaxis]
  • pallor, general malaise, palpitation or shortness of breath in climbing up stairs or walking up a slope [pure red-cell aplasia]
  • chest pain, cold sweat, chest pressure [myocardial infarction]
  • chest pain, dyspnea, disturbed consciousness [pulmonary infarction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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