くすりのしおり

Injection
Published: 2/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
NAFAMOSTAT for Injection 100 "MEEK"
 Active ingredient:
Nafamostat mesilate
 Dosage form:
Injection
 Print on wrapping:

Effects of this medicine

This medicine improves visceral disorders and bleeding tendency caused by blood clotting tendency in the vessels. It prevents coagulation in the blood circuit during hemodialysis.
It is usually used to prevent disseminated intravascular coagulation (DIC) and clotting of perfusing blood in extracorporeal blood circuit.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Disseminated intravascular coagulation (DIC): In general, this medicine is injected by continuous intravenous infusion over a period of 24 hours.
    Prevention of perfusing blood coagulation in extracorporeal blood circuit: In general, the inside of blood circuit is rinsed and filled prior to the start of extracorporeal circulation and then this medicine is continuously injected through an anticoagulant injection line after start of extracorporeal circulation.
  • The treatment period with this medicine is determined based on your symptoms.

Precautions while taking this medicine

  • Since hyperpotassemia or hyponatremia may occur, your serum potassium and serum sodium values are periodically checked. Keep all appointments/laboratory test schedules.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, erythema, itching and bleeding tendency. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • decreased blood pressure, conscious disorder, respiratory distress [shock, anaphylactoid symptoms]
  • weakness, numbness of limbs and lips, paralysis of limbs [hyperpotassemia]
  • nausea, convulsion, headache [hyponatremia]
  • nose/gum bleeding, subcutaneous bleeding of limbs, etc. [thrombocytopenia]
  • sore throat, fever, headache [leukopenia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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