くすりのしおり

Internal
Revised: 3/2007

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
BENIDIPINE HYDROCHLORIDE Tablets 2 "MEEK"
 Active ingredient:
Benidipine hydrochloride
 Dosage form:
yellow tablet (diameter: about 6.1 mm, thickness: about 2.7 mm)
 Print on wrapping:
MK18

Effects of this medicine

This medicine inhibits the calcium channel of vascular smooth muscles and dilates small arteries to lower blood pressure. It also has an antianginal effect and a renal function-improving effect.
It is usually used to treat hypertension, renal parenchymal hypertension and angina pectoris.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have cardiogenic shock, hypotension or liver dysfunction.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Hypertension or renal parenchymal hypertension: In general, for adults, take 1 to 2 tablets (2 to 4 mg of the active ingredient) at a time, once a day after breakfast. The dosage may be adjusted according to the disease, age or symptoms. If this medicine does not work enough, the dosage may be increased up to 4 tablets (8 mg) once a day. For treatment of severe hypertension, take 2 to 4 tablets (4 to 8 mg) at a time, once a day before breakfast. Strictly follow the instructions.
  • Angina pectoris: In general, for adults, take 2 tablets (4 mg of the active ingredient) at a time, twice a day, after breakfast and dinner. The dosage may be adjusted according to the age or symptoms. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If there is less than 6 hours to the next dose for treatment of hypertension or if it is almost time for the next dose for treatment of angina pectoris, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness, etc. Take care in driving a car, working at heights or engaging in operation of dangerous machinery.
  • Avoid taking grapefruit juice with this medicine, since it may intensify the therapeutic effects of this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, pruritus, photosensitivity and gynecomastia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • general malaise, diarrhea, yellowing of the skin and the white of eyes [liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Seek advice of your pharmacy or medical institution about proper disposal of the unused medicines.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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