くすりのしおり

Internal
Revised: 4/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
PAROXETINE Tablets 10mg "MEIJI"
 Active ingredient:
Paroxetine hydrochloride hydrate
 Dosage form:
reddish white tablet with split line, diameter: 7.1 mm, thickness: 3.2 mm
 Print on wrapping:
パロキセチン10mg「明治」, MS022, PAROXETINE10mg「MEIJI」

Effects of this medicine

This medicine acts on a brain transmitter (serotonin) to exert its antidepressive and antianxiety effects, thereby improving symptoms such as a depressive mood, anxiety, irritability, loss of motivation, loss of appetite, sleeplessness, abrupt onset of anxiety, obsession and excessive anxiety and tension in public.
It is usually used to treat depression/depressive state, panic disorder, obsessive-compulsive disorder, social anxiety disorder and post-traumatic stress disorder.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: manic depressive psychosis, a history of suicidal ideation or suicidal attempt, suicidal ideation, predisposition to organic brain disorder or schizophrenia, highly impulsive comorbidity, a history of epilepsy, glaucoma, bleeding tendency or bleeding diathesis.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Depression/depressive state: In general, for adults, take 20 to 40 mg of paroxetine at a time, once a day, after an evening meal. Start with 10 to 20 mg at a time and the dosage will be increased by 10 mg per day at weekly intervals in principle. The dosage may be adjusted according to the symptoms within the range not exceeding 40 mg a day.
    Panic disorder: In general, for adults, take 30 mg of paroxetine at a time, once a day, after an evening meal. Start with 10 mg at a time and the dosage will be increased by 10 mg per day at weekly intervals in principle. The dosage may be adjusted according to the symptoms within the range not exceeding 30 mg a day.
    Obsessive-compulsive disorder: In general, for adults, take 40 mg of paroxetine at a time, once a day, after an evening meal. Start with 20 mg at a time and the dosage will be increased by 10 mg per day at weekly intervals in principle. The dosage may be adjusted according to the symptoms within the range not exceeding 50 mg a day.
    Social anxiety disorder: In general, for adults, take 20 mg of paroxetine at a time, once a day, after an evening meal. Start with 10 mg at a time and the dosage will be increased by 10 mg per day at weekly intervals in principle. The dosage may be adjusted according to the symptoms within the range not exceeding 40 mg a day.
    Post-traumatic stress disorder: In general, for adults, take 20 mg of paroxetine at a time, once a day, after an evening meal. Start with 10 to 20 mg at a time and the dosage will be increased by 10 mg per day at weekly intervals in principle. The dosage may be adjusted according to the symptoms within the range not exceeding 40 mg a day.
    This preparation contains 10 mg of paroxetine in a tablet. In any case, strictly follow the instructions.
  • You may have to take this medicine usually for about 2 weeks before you begin to feel better. It is important for you to continue this medicine even after you begin to feel better.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so. If you abruptly stop taking this medicine or reduce the dose, symptoms you can hardly tolerate such as dizziness, nausea and sweating may appear. Absolutely avoid stopping the medication or reducing the dose.

Precautions while taking this medicine

  • This medicine may cause sleepiness and dizziness. Pay close attention when operating dangerous machinery, such as driving a car.
  • Avoid drinking alcohol while taking this medicine, because it may intensify the effect of this medicine.
  • Pay attention when taking any food containing St. John's wort (a kind of herb) with this medicine, since it may intensify the effect of this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, sleepiness, dry mouth, dizziness, constipation and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • anxiety, excitement, shivering of hands [serotonin syndrome]
  • abrupt onset of a fever, muscle stiffness, consciousness disorder [neuroleptic malignant syndrome]
  • impaired mind, seeing thing or hearing sound that does not really exist, a state of paroxysmal muscular contraction [confusion, hallucination, delirium, convulsion]
  • convulsion, decreased consciousness, headache [syndrome of inappropriate ADH (antidiuretic hormone) secretion]
  • general malaise, yellowing of the white of eyes, loss of appetite [liver dysfunction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Seek advice of your pharmacy or medical institution about proper disposal of the unused medicines.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

Keywords Search

 

 

 

 

Advanced Search

Browse by drug name A-Z
Browse by drug name A-Z