くすりのしおり

Internal
Revised: 4/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ALLOPURINOL TABLETS 50mg "NISSIN"
 Active ingredient:
Allopurinol
 Dosage form:
white to slightly yellowish white tablet, diameter : 6.5 mm, thickness : 2.2 mm
 Print on wrapping:
(front) アロプリノール錠50mg「日新」, アロプリノール, NS343, 50mg, (back) Allopurinol Tab.50mg "NISSIN", アロプリノール「日新」, 50mg, 高尿酸血症のくすり

Effects of this medicine

This medicine suppresses uric acid production in body to lower the amount of uric acid in blood.
It is usually used to improve hyperuricemia in gout or hypertension accompanied by hyperuricemia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: hepatic disorder, history of hepatic disorder or renal function disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 4 to 6 tablets (200 to 300 mg of the active ingredient) a day, in 2 to 3 divided doses, after meals. The dosage may be adjusted according to age and symptoms. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • When you start taking this medicine, gout attack (pain) may temporarily get worse. However do not adjust the dosage or stop taking this medicine yourself. If such symptoms occur, consult with your doctor.
    Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • If you have not heart and renal disorder, take adequate amount of water to increase urine formation.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itch, joint pain, anemia, purpura, renal dysfunction (headache, swelling of face, eyes puffy, decreased urine output, etc.), loss of appetite, gastric distress, loose stool, diarrhea, general malaise and loss of hair. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever, rash, joint pain [toxic epidermal necrolysis, mucocutaneous-ocular syndrome, severe skin disorder such as exfoliative dermatitis, hypersensitivity vasculitis]
  • rash, fever, lymphadenopathy [drug-induced hypersensitivity]
  • abnormal pulse, respiratory distress, pale face [shock, anaphylaxis]
  • anemic symptoms, fever, bleeding tendency [aplastic anemia, pancytopenia, agranulocytosis, thrombocytopenia]
  • general malaise, vomiting, yellowing of the skin [serious liver dysfunction such as severe hepatitis, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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