くすりのしおり

Internal
Revised: 12/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
RANITIDINE TABLETS 150mg "YD"
 Active ingredient:
Ranitidine hydrochloride
 Dosage form:
white tablet, diameter 9 mm, thick 4 mm
 Print on wrapping:
(front) ラニチジン錠150mg「YD」, 150mg, ラニチジン, (back) RANITIDINE 150mg, ラニチジン錠150mg「YD」, 150mg, H2ブロッカー, YD869

Effects of this medicine

This medicine blocks the histamine receptors of the gastric mucosa associated with gastric-acid secretion, thus suppress the secretion of gastric-acid, and consequently prevents autodigestion of gastric mucosa, gastric wall and duodenum.
It is usually used in the treatment of gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger-Ellison syndrome, reflux esophagitis, upper gastrointestinal bleeding, acute gastritis and acute exacerbation phase of chronic gastritis, and also used for anesthetic premedication.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have renal disorder or hepatic disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger-Ellison syndrome, reflux esophagitis and upper gastrointestinal hemorrhage: In general, for adults, take 1 tablet (150 mg of ranitidine) at a time, twice a day, after breakfast and before bedtime. The dosage may be changed to 2 tablets (300 mg) at a time, once a day, before bedtime. The dosage may be adjusted according to symptoms.
    For the improvement of gastric mucosal lesions in acute gastritis and acute exacerbation of chronic gastritis: In general, for adults, take 75 mg of ranitidine at a time, twice a day, after breakfast and before bedtime. The dosage may be changed to 150 mg at a time, once a day, before bedtime. The dosage may be adjusted according to symptoms. This medicine contains 150 mg of ranitidine in a tablet.
    Anesthetic premedication: In general, for adults, take 1 tablet (150 mg of ranitidine) at a time, twice, before bedtime of the previous day and before 2 hours of anesthesia on the day of surgery.
    Strictly follow the instructions in any case.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itch, fever, angioedema (swelling of eyelid/lips), vasculitis (bruise on limbs skin), constipation, diarrhea, headache, nausea and vomiting. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, general blushing, blood-pressure decreased [shock, anaphylaxis]
  • fever, malaise, nose/gum bleeding [aplastic anemia, pancytopenia, agranulocytosis, thrombocytopenia]
  • general malaise, loss of appetite, yellowing of the skin and the whites of the eyes [liver dysfunction, jaundice]
  • limbs muscular pain/stiffness, numbness/lassitude, reddish brown urine [rhabdomyolysis]
  • defective judgment, loss of consciousness, convulsion [disturbance of consciousness, convulsion, myoclonus]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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