くすりのしおり

Internal
Revised: 11/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
HERBESSER Tablets 60
 Active ingredient:
Diltiazem hydrochloride
 Dosage form:
white tablet, diameter: 8.0 mm, thickness: 3.5 mm
 Print on wrapping:
ヘルベッサー60mg, HERBESSER, TA125

Effects of this medicine

This medicine has calcium antagonistic action to inhibit calcium ion influx of extracellular fluid into cells, and thereby dilates coronary artery and peripheral blood vessels, reduces blood pressure and the frequency of angina attacks.
It is usually used to treat hypertension and angina pectoris.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have congestive cardiac failure, second-degree or higher atrioventricular (AV) block, or sick sinus syndrome (with persistent sinus bradycardia at less than 50 beats/minute, sinus arrest, sinoatrial block, etc.)
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Angina pectoris, variant angina : In general, for adults, take 30 mg of the active ingredient at a time, three times a day. If the effect is insufficient, the dose may be increased to 60 mg at a time, three times a day.
    Essential hypertension (mild to moderate) : In general, for adults, take 30 to 60 mg at a time, three times a day. It should be adjusted according to your age and symptoms.
    This preparation contains 60 mg of the active ingredient in a tablet.
    In any case, strictly follow the instructions.
  • Since this medicine is an extended-release formulation, take it without chewing.
  • If you miss a dose, take a dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness due to decreased blood pressure. Avoid performing dangerous operations such as driving a car, operating machinery or working at heights.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include stomach discomfort, constipation, abdominal pain, dizziness, bradycardia, AV block (skipped pulse beats), facial flushing, and hypersensitivity(rash, itch, hives, photosensitivity) and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • slow pulse, general malaise/shortness of breath, dizziness/syncope [complete AV block, severe bradycardia]
  • respiratory distress, general edema, fatiguability [congestive cardiac failure]
  • high fever over 38 degrees Celsius, bloodshot eyes, erosion of lip, rash and blister on skin and mucous membranes, red skin in vast area, pus filled blister [oculomucocutaneous syndrome, toxic epidermal necrolysis, erythroderma (exfoliative dermatitis), acute generalised exanthematous pustulosis]
  • general malaise, loss of appetite, yellowing of the skin and the whites of eyes [hepatic function disorder, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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