くすりのしおり

Internal
Published: 12/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
VALACICLOVIR TABLETS 500 mg "TOWA"
 Active ingredient:
Valaciclovir hydrochloride
 Dosage form:
white to slightly yellowish white tablet, major axis: 17.6 mm, minor axis: 8.2 mm, thickness :6.0 mm
 Print on wrapping:
Tw027, バラシクロビル500 mg「トーワ」, 500mg, 単純疱疹, 帯状疱疹または水痘の薬

Effects of this medicine

This medicine suppresses the growth of herpes simplex/varicella/herpes zoster viruses.
It is usually used to treat herpes simplex, herpes zoster and varicella and to prevent recurrence of genital herpes.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have renal disease.
    If you are receiving hemodialysis..
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Herpes simplex : In general, for adults, take 1 tablet (500 mg of valaciclovir) at a time, twice a day.
    Herpes zoster : In general, for adults, take 2 tablets (1,000 mg of valaciclovir) at a time, 3 times a day.
    To prevent recurrence of genital herpes : In general, for adults, take 1 tablet (500 mg of valaciclovir) at a time, once a day. The dosage and frequency of doses may be adjusted according to symptoms of the patient.
    Varicella : In general, for adults and children of 40 kg or more, take 2 tablets (1,000 mg of valaciclovir) at a time, 3 times a day.
    In any case, the dosage and frequency of doses may adjusted according to the underlying disease of the patient. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Please take a larger amount of water than usual while you are on this medicine. However, if you have been instructed to restrict fluid intake, please consult with your doctor or pharmacist.
  • This medicine may cause disturbance of consciousness. Take extra care when operating dangerous machinery, such as when driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include headache, decreased consciousness including sleepiness, abdominal pain, nausea, diarrhea, rash, hives, itch, and photosensitivity. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • breathing difficulty, angioedema, generalized flush [anaphylactic shock, anaphylaxis]
  • fever, general malaise, bleeding tendency [pancytopenia, agranulocytosis, thrombocytopenia, disseminated intravascular coagulation, thrombocytopenic purpura]
  • edema, decrease of urine output, headache [acute renal failure]
  • disturbance of consciousness (coma), hallucination, convulsion [neuropsychiatric symptom]
  • fever, erythema, hyperemia of the eye [toxic epidermal necrolysis, Stevens-Johnson syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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